Protein Info for Ac3H11_2460 in Acidovorax sp. GW101-3H11

Annotation: DinG family ATP-dependent helicase YoaA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 PF06733: DEAD_2" amino acids 176 to 251 (76 residues), 22.3 bits, see alignment E=1.4e-08 PF13307: Helicase_C_2" amino acids 492 to 657 (166 residues), 138 bits, see alignment E=5.2e-44

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 69% identity to vap:Vapar_2178)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KUR9 at UniProt or InterPro

Protein Sequence (686 amino acids)

>Ac3H11_2460 DinG family ATP-dependent helicase YoaA (Acidovorax sp. GW101-3H11)
MALVDMVAEVFAAGGVLERADTHFQPREGQTQMACAVARTIEAGGALVVEAGTGVGKTFS
YLVPALLSGERVLLSTATKALQDQLFARDLPWLVETLGMPVRMALLKGRSSYLCLYRMEL
ARQDAQAQDRGVARVLAKVEDWSHHTQSGDLAELTGLDDRSPVIPLVTSTRENCLGSQCA
QFRPCHVHRARREALAADIVVINHHLFFADVAVRESGMAELLPTVRVVVFDEAHQINETG
VQFLGTQLSTGQVMDFSRDLLAAGLQHARGLADWVELSRRVELSAQDLRLVARTALGATK
LRWADDAPEGIPAEHWHGALRGVALACAQAQEALDTVSEIAPDFVRLYERGSELLARLAR
FSGPGDPEVVRWVDVGTQLRLVESPLDIAEAMRTRLLGAPAEASEDAGGDGWPGDSPAGP
GRAWVFTSATLGDDERLSWFTERAGLQEAEILRVVSPFDYPAQAALYVPRHLPAPADPAH
SLALAQWVGQAAEQLGGRTLVLTTTLKALRAVGDALQKRFASSGALEVLVQGEWPKRRLM
ERFREGADHGQPGCVLVASATFWEGFDVPGDALQLVVIDKLPFPPPGDPLVEARTQRIEK
AGGKAFKAYALPEAAVALKQGAGRLIRRESDRGILVVGDTRLVTMGYGKRLLAALPPMRR
LESEEAFEDALQALLTRPSTTDPTCP