Protein Info for Ac3H11_2411 in Acidovorax sp. GW101-3H11

Annotation: Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 601 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 63 to 81 (19 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details amino acids 177 to 197 (21 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 314 to 334 (21 residues), see Phobius details amino acids 367 to 388 (22 residues), see Phobius details amino acids 394 to 414 (21 residues), see Phobius details amino acids 419 to 438 (20 residues), see Phobius details amino acids 459 to 478 (20 residues), see Phobius details amino acids 523 to 545 (23 residues), see Phobius details amino acids 565 to 585 (21 residues), see Phobius details PF03814: KdpA" amino acids 11 to 596 (586 residues), 782.1 bits, see alignment E=1.1e-239 TIGR00680: K+-transporting ATPase, A subunit" amino acids 242 to 597 (356 residues), 553.6 bits, see alignment E=2.5e-170

Best Hits

Swiss-Prot: 80% identical to KDPA_ACIAC: Potassium-transporting ATPase potassium-binding subunit (kdpA) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K01546, K+-transporting ATPase ATPase A chain [EC: 3.6.3.12] (inferred from 80% identity to aav:Aave_0355)

Predicted SEED Role

"Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KTV7 at UniProt or InterPro

Protein Sequence (601 amino acids)

>Ac3H11_2411 Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1) (Acidovorax sp. GW101-3H11)
MDTSAWSLMGLFLMVLGVLAWPLGKWLAAVCEGRLPRWMHAAEKPLYKLAGVAPDQMMHW
RSYALALLAFNAIGAFAVYGLQRLQHLLPLNPQGMAAVSGDSSFNTAISFVSNTNWQGYG
GESTMSYLTQMLGLSVQNFFSAATGIAVAFALARGFAARSTDGQGFVGNFWADVTRITAW
VLVPIAFVISMVLVGQGGIQNFDAYKDVATLEPTAYDVPKLDASGQPVVGSDGAPVMEAK
TSNTQTLAMGPVASQEAIKMLGTNGGGFFNANSAHPYENPTALTNFVQMLAIFLIPAALC
FAFGRVVGDQRQGFAILAAMTVMFVVAVIAVVSAEKAGNPQWVGLGVEQTASALQAGGNM
EGKEVRFGINASALFAAVTTAASCGAVNAMHDSFTPLGGMVPLVLMQLGEVVFGGVGTGL
YGMLVFAILAVFMAGLMIGRTPEYLGKKIEVREMKLTSAAILVTPILVLVGTAIAVATDA
GRAGIANPGAHGFSEILYALTSAANNNGSAFAGLSANTPFYNVLLGLAMWLGRFGVIVPV
LAIAGSLAAKKRLPVTAGTMPTHGPLFVTLLIGTVLLVGLLNYVPSLALGPMVEHLMLRV
Q