Protein Info for Ac3H11_2060 in Acidovorax sp. GW101-3H11

Annotation: two-component system, sensor protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 169 to 189 (21 residues), see Phobius details PF08521: 2CSK_N" amino acids 22 to 165 (144 residues), 122.8 bits, see alignment E=1.7e-39 PF00512: HisKA" amino acids 250 to 312 (63 residues), 47.9 bits, see alignment E=1.7e-16 PF02518: HATPase_c" amino acids 356 to 463 (108 residues), 78.9 bits, see alignment E=5.9e-26

Best Hits

KEGG orthology group: None (inferred from 63% identity to rfr:Rfer_1092)

Predicted SEED Role

"two-component system, sensor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KPW8 at UniProt or InterPro

Protein Sequence (464 amino acids)

>Ac3H11_2060 two-component system, sensor protein (Acidovorax sp. GW101-3H11)
MRHVPGVSLQRKLLLWLLLPQLVLWLSGGFLAWRIALQNGEKGIDQTLTQSVRALARQIK
PIGDGLLVDFPKAAQDILEQDPADRITYMVSSPPGRFLLGNAQLPPPPPVEVRVGDPYLY
HARVDDRPVRVALLDVDYGTASTRQRLRVQVAQSLTVRERIAQELLEQMVFPMGLMGLAL
SAVVYAGVLRGLQPLKRLEAQIERAGARPHTGTTPLLPIELTSAPQEVHSLASTINRLLE
TVARGQQKEKRFLNDAAHQLRTPLAGLIGQTELALHESHEPAVQARLQKVLSAAQRSAHL
VHQLLQLARSESNVEMQPIDLAALAREVAREWAARALAQGMDLGYEGDDSLPVQGHPLLL
REALNNLIDNALHYAGPGATVTVRVGHEEPGRWALLVVEDDGPGVPAEHLGDLFARFWRG
SDKAGGCGLGLSIVEEIALRHGGRTVAEGMVPKGLRVGIRVPAG