Protein Info for Ac3H11_2055 in Acidovorax sp. GW101-3H11

Annotation: Probable transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 243 to 262 (20 residues), see Phobius details PF01418: HTH_6" amino acids 1 to 74 (74 residues), 65.4 bits, see alignment E=5.7e-22 PF01380: SIS" amino acids 131 to 253 (123 residues), 69.7 bits, see alignment E=3.3e-23

Best Hits

Swiss-Prot: 40% identical to HEXR_ECOLI: HTH-type transcriptional regulator HexR (hexR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to xtr:100496205)

Predicted SEED Role

"Probable transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KPN2 at UniProt or InterPro

Protein Sequence (281 amino acids)

>Ac3H11_2055 Probable transcriptional regulator (Acidovorax sp. GW101-3H11)
MLDRITASLSSLAPAEQRVAKLVLADPRSFARLPVRELAERAHVSKPTVVRFCRSMGYDG
LADFKLKLAGSVSEGVPFIHRSVDVDDKTGDVLVKVVDNAVAAFLQYRNAASTVALERAA
EAIAATWQTGKRIEFYGVGNSGIVAQDAQHKFFRLGVTSIATSDGHMQVMSATLLGPGDC
AVIISNSGRTRDLMDAADIARKNGATTIAITASGSPLASTCQIHLAADHPEGYDRYSPMV
SRLMHLLIIDVLATCVALRIGGSLQPILQQMKENLRAKRYA