Protein Info for Ac3H11_2001 in Acidovorax sp. GW101-3H11

Annotation: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF02492: cobW" amino acids 5 to 185 (181 residues), 195.9 bits, see alignment E=4.9e-62 PF07683: CobW_C" amino acids 258 to 350 (93 residues), 78.2 bits, see alignment E=3.6e-26

Best Hits

KEGG orthology group: None (inferred from 91% identity to aaa:Acav_0738)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KNJ4 at UniProt or InterPro

Protein Sequence (353 amino acids)

>Ac3H11_2001 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family (Acidovorax sp. GW101-3H11)
MALIPVTILTGFLGSGKTTLLKRLLSEAHGQKIAVIENEFGEENIDNDILVTESKEQIVQ
MSNGCICCTIREDLRETLQLLAAKKRKNLLEFDRIVIETTGVADPGPVAQTFFMEEEIAE
TYLIDSIITLVDAKHAPQQLNDRQEARRQVGFADQIFLSKTDLVSAEETDALIHRLKHMN
PRAPIKAVHFGEVPLKEVLDLRGFNLNAKLDIDPDFLKEEGDGHDHHDHDHEHGEHCSHP
SHQHDHGHGHHHHHDDDVKSFVYRSERPFDPAKLEDFLGAIVNIYGPRMLRYKGVLNMKG
TERKVIFQGVHQLMGSDLGPQWAEGEPRVSKMVFIGIDLPKDIFLQGLEQSLV