Protein Info for Ac3H11_1813 in Acidovorax sp. GW101-3H11

Annotation: CRISPR-associated protein Cas1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 237 to 257 (21 residues), see Phobius details TIGR03637: CRISPR-associated endonuclease Cas1, subtype I-F/YPEST" amino acids 18 to 322 (305 residues), 504.9 bits, see alignment E=8.8e-156 TIGR00287: CRISPR-associated endonuclease Cas1" amino acids 25 to 297 (273 residues), 206.7 bits, see alignment E=4.8e-65 PF01867: Cas_Cas1" amino acids 54 to 276 (223 residues), 39.6 bits, see alignment E=1.9e-14

Best Hits

Swiss-Prot: 74% identical to CAS1_PSEAB: CRISPR-associated endonuclease Cas1 (cas1) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: None (inferred from 87% identity to vei:Veis_1460)

Predicted SEED Role

"CRISPR-associated protein Cas1" in subsystem CRISPRs

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KIV2 at UniProt or InterPro

Protein Sequence (335 amino acids)

>Ac3H11_1813 CRISPR-associated protein Cas1 (Acidovorax sp. GW101-3H11)
LVKTDAMESIASSDLKTILHSKRANLYYLEHCRVLVNGGRVEYVTDTGKRSLYWNIPIAN
TTSILLGTGTSITQAAMRELAKAGVLVGFAGGGGTPLFSANEVDIEVAWFAPQSEYRPTE
YLQAWVKFWFDDDLRLMAAKALQTARLQRLREQWLQRPLREAGFAVDAPRLEALIGQFTQ
RIATAPDVTALLTDEAQLTKALFKLAVDATQYGEFTRAKRGSGTDAANRFLDHGNYLAYG
LGATATWVLGLPHGLAVLHGKTRRGGLVFDAADLVKDAAILPQAFLSAMQGDDEQQFRRR
CIDTLTQSDSLDFMIDTLKLIAITTAQHATARPAP