Protein Info for Ac3H11_1705 in Acidovorax sp. GW101-3H11

Annotation: Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 transmembrane" amino acids 24 to 47 (24 residues), see Phobius details amino acids 148 to 171 (24 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details PF00487: FA_desaturase" amino acids 25 to 228 (204 residues), 62.1 bits, see alignment E=7.3e-21 PF01610: DDE_Tnp_ISL3" amino acids 281 to 400 (120 residues), 30.1 bits, see alignment E=4.3e-11

Best Hits

KEGG orthology group: K00507, stearoyl-CoA desaturase (delta-9 desaturase) [EC: 1.14.19.1] (inferred from 85% identity to ajs:Ajs_3386)

Predicted SEED Role

"Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)" (EC 1.14.19.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.19.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KCH5 at UniProt or InterPro

Protein Sequence (404 amino acids)

>Ac3H11_1705 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) (Acidovorax sp. GW101-3H11)
MLLPDWAVLNAAIDWLGHGLWNLAWWQIVLYTLATTHITIAAVTIFLHRAQAHRALDLHA
IPSHFFRFWLWIGTGMVTKEWVAIHRKHHAKCETVDDPHSPQTRGLDTVMWRGAELYRAE
SKNLETMKKFGHGTPDDWMERNVYTRFGWQGVGLMLVLNLALFGAVGAAVWAVQMLWIPF
WAAGVVNGIGHYWGYRNFEAQDASTNLSPWGVIIGGEELHNNHHTYPTSAKFSVKPYEFD
IGWAYISLMKKVGWATVKKVPPKLQLGDVKAVADEKTLEALIANRYEVMAGYARGVRQAC
KEEIAALKARQADVSVLKAAKRWLPRDAEKIPAVALPQLAQARAAHPALDKMVTMREELR
QLWLNTSQSREQLTADLQAWCRRAEESGISALREFSLRLRAAQA