Protein Info for Ac3H11_1531 in Acidovorax sp. GW101-3H11

Annotation: Translation initiation factor 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 861 transmembrane" amino acids 454 to 473 (20 residues), see Phobius details TIGR03505: FimV N-terminal domain" amino acids 185 to 256 (72 residues), 70.5 bits, see alignment E=7.9e-24 TIGR03504: FimV C-terminal domain" amino acids 817 to 860 (44 residues), 47.8 bits, see alignment 1.1e-16

Best Hits

KEGG orthology group: K07288, uncharacterized membrane protein (inferred from 61% identity to aav:Aave_1218)

Predicted SEED Role

"Translation initiation factor 2" in subsystem NusA-TFII Cluster or Translation initiation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K8F5 at UniProt or InterPro

Protein Sequence (861 amino acids)

>Ac3H11_1531 Translation initiation factor 2 (Acidovorax sp. GW101-3H11)
VACSGFYASDASALALGRITVQSALGEPLRAEIDLPQITPAEADTLRATAAAPEVFRAQG
MEYTQAMNNLQIQLQRRPDGTAVLRLTSDRPVNEPFLDLVLDANWGTGRLVRSYTMLFDP
PALRRPAPAVTASPQISAPAVQAAPAVRAPAAPRPTESAAAPAAPRPAAAPRPTPTDGVT
VQAGDTAGRLANSYKPAGVSLDQMLVAMMRANPDAFIQGNVNRIKAGAVLQMPDEAAAQS
TTVPEARQILAAQARDFNDFRRKLAGAAPSTEVAAAQRSASGSVQTRVEDKKPATAAPDK
LTLSKGSVKGQKAAEEQVAKDKQAGEAATRMAELSKNITDLNKLGAASSATGGSAAPAAA
GAASAPAGVAVQAPAVPATPTAPPAPEAPASAPAAAASAPAEASVPAEAAASAPAAEASA
PAPAPAPAPVPTPAPAPAPVEEPGLLAGLIDDPLLPIGGLLVAGALGFVAYRVVQRRRQN
NGVDSSFLESRIQPDSFFGASGGQRVDTANSDMTTGSSMAYSPSQLDAGGDVDPVAEADV
YLAYGRDLQAEEILKEAVRHNPGRVSVHVKLGEIYAKRQDRKALEAVAGEVFKLTQGEGP
DWARIAELGHDLEPDNRLYQPGGRPGMGEDESPSLPPGGFPSTFTGAGSTADAALPPDLD
LDLDLDLPDDALTDAPPAAPGGFAAAAAAATSARGNTPSDADEPPTLRPELDLPPPSAEP
PAAWNSPDTSPSPMAPPPVADLDFPSADDLSMAPSGPMPLTGDAKDSGPMEFDLGELSLD
LNAPTKPMAAPAAKAPAPVADSSDDGSAAAQDDPLATKLALAEEFNAIGDTDGARTLIEE
VVAESSGALKTRAQRMLAELG