Protein Info for Ac3H11_1453 in Acidovorax sp. GW101-3H11

Annotation: Preprotein translocase subunit SecG (TC 3.A.5.1.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 120 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 54 to 77 (24 residues), see Phobius details TIGR00810: preprotein translocase, SecG subunit" amino acids 6 to 76 (71 residues), 87.3 bits, see alignment E=2.7e-29 PF03840: SecG" amino acids 7 to 76 (70 residues), 75.7 bits, see alignment E=1.3e-25

Best Hits

Swiss-Prot: 45% identical to SECG_ECO57: Protein-export membrane protein SecG (secG) from Escherichia coli O157:H7

KEGG orthology group: K03075, preprotein translocase subunit SecG (inferred from 80% identity to aaa:Acav_1281)

MetaCyc: 45% identical to Sec translocon subunit SecG (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase subunit SecG (TC 3.A.5.1.1)" in subsystem Murein hydrolase regulation and cell death (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K6R9 at UniProt or InterPro

Protein Sequence (120 amino acids)

>Ac3H11_1453 Preprotein translocase subunit SecG (TC 3.A.5.1.1) (Acidovorax sp. GW101-3H11)
MNVIVNVILAVQMLAALVMIGLILIQHGKGADMGAAFGSGSSGSLFGASGSANFLSRSTG
VLAAVFFVSTLALAYFGNARPASSGSVLEAPAAVAPAAAAPDAAVAPAVPASGAAQIPTK