Protein Info for Ac3H11_1263 in Acidovorax sp. GW101-3H11

Annotation: Response regulator receiver:Transcriptional regulatory protein, C- terminal

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF00072: Response_reg" amino acids 3 to 114 (112 residues), 94.9 bits, see alignment E=3.6e-31 PF00486: Trans_reg_C" amino acids 146 to 219 (74 residues), 78 bits, see alignment E=4.6e-26

Best Hits

Swiss-Prot: 48% identical to TCTD_SALTY: Transcriptional regulatory protein tctD (tctD) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02483, two-component system, OmpR family, response regulator (inferred from 92% identity to pna:Pnap_3958)

Predicted SEED Role

"Response regulator receiver:Transcriptional regulatory protein, C- terminal"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LCV3 at UniProt or InterPro

Protein Sequence (224 amino acids)

>Ac3H11_1263 Response regulator receiver:Transcriptional regulatory protein, C- terminal (Acidovorax sp. GW101-3H11)
MRILIAEDDQVLADGLLRTLRASGAVVDHVASGTEADAALMTNNEFDLLILDLGLPKMHG
LEVLKKLRSRGSALPVLILTAADSVEERVKGLDFGADDYMAKPFSLQELEARVRALTRRG
MGGTSSSIKHGPLVYDQAGRVATIDGKMIELSARELGLLEVLLQRAGRLVSKEQLVERLC
EWGEEVSNNAIEVYIHRLRKKIEGGPIRIATVRGLGYCLEKIPG