Protein Info for Ac3H11_1206 in Acidovorax sp. GW101-3H11

Annotation: Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 267 to 288 (22 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 306 to 428 (123 residues), 76.1 bits, see alignment E=1.3e-25 PF00989: PAS" amino acids 307 to 420 (114 residues), 57.7 bits, see alignment E=2.8e-19 PF08448: PAS_4" amino acids 315 to 425 (111 residues), 34.9 bits, see alignment E=3.9e-12 PF13426: PAS_9" amino acids 323 to 422 (100 residues), 51.1 bits, see alignment E=3.6e-17 PF02518: HATPase_c" amino acids 578 to 691 (114 residues), 81.5 bits, see alignment E=1.6e-26

Best Hits

KEGG orthology group: K11711, two-component system, LuxR family, sensor histidine kinase DctS [EC: 2.7.13.3] (inferred from 64% identity to pol:Bpro_4653)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LBJ2 at UniProt or InterPro

Protein Sequence (697 amino acids)

>Ac3H11_1206 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY (Acidovorax sp. GW101-3H11)
VTEPRAPRPPRTLLQRWRGAWRRWSLWTALVLLVVSMLATMVWLAGRYEASQVQTRLERD
AADAVSDIRTALTHNLQSLQALPADAPGQLAWEVEASELLRIRRELVRIEWRDAHLKLRT
HVQSPYRPVAWDMRLRDSSQSDLTIACTNARRLGSPAYSTSYFQPHGDGLGSEMMELCVP
LTAGGRTTGFLVATYGLQDILLNLVAHNLTRSQEASFTEPDGTRLAVMGAARRGSRMFTA
QHLLDLPGATLVLRMDGWHTAPSVFPNVLTALVTAMSIALVTVMVVLVRDNRRRLRAERD
LADALAFRKAMEDSLVTGLRARDLQGRITYVNPAFCEMVGFAPQELLGLSMSAPYWPPER
VEEYQQRQAIRFAGTMPPREGFESEFMRKDGTRFPVLIIEAPLINAQGQHTGWMSAFLDI
SEQRRVEELSRASQERLQATARLATVGEMASLLSHELNQPLAAISSYANGSLNLLEQQAT
PAPTSASVPPDTSAAPPTPDALDDVRMAMRQIARQAERAGRVIKSVHDFVRRRDQAREAV
HAQQLLDAILPLVSLQARKLGVRVHTTVEPGLPPTLCDRTMVEQVLLNLARNAMQAMDDP
AVRSRVLDIRVRHAASSQHSGWVEFVVTDQGTGIPPEVAAKLFTPFFTTRPEGMGLGLSM
CRTVIEQHGGFLGFAPNEPRGTVFTFTLPASQPDSRP