Protein Info for AZOBR_RS28110 in Azospirillum brasilense Sp245

Annotation: C4-dicarboxylate ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 154 to 177 (24 residues), see Phobius details amino acids 197 to 220 (24 residues), see Phobius details amino acids 232 to 256 (25 residues), see Phobius details amino acids 318 to 352 (35 residues), see Phobius details amino acids 364 to 387 (24 residues), see Phobius details amino acids 397 to 414 (18 residues), see Phobius details PF00375: SDF" amino acids 22 to 412 (391 residues), 353.3 bits, see alignment E=8.9e-110

Best Hits

Swiss-Prot: 59% identical to DCTA_LARHH: C4-dicarboxylate transport protein (dctA) from Laribacter hongkongensis (strain HLHK9)

KEGG orthology group: None (inferred from 62% identity to azc:AZC_2673)

MetaCyc: 54% identical to C4 dicarboxylate/orotate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-121A; TRANS-RXN-121C; TRANS-RXN-122A; TRANS-RXN0-451; TRANS-RXN0-517; TRANS-RXN0-553

Predicted SEED Role

"C4-dicarboxylate transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AXX0 at UniProt or InterPro

Protein Sequence (457 amino acids)

>AZOBR_RS28110 C4-dicarboxylate ABC transporter (Azospirillum brasilense Sp245)
MRLQTGEQTPAPTKPKAFYKALYFQVVVGLTLGILAGHFWPDLGASLKPLGDGFVKLVKM
MIAPVVFCTIVSGITSLNDTREIGKTLVKSMALFYALTVAALLIGLAAVMIIEPGVGMHV
SAASLDPTVAARYAKQAAPVGFTDFVLHIIPHSFFGAFAEGEVLPVLLISVLVGFGLTRV
GKAGEPVVQGIESFSHVLFAAFGFIMKLAPIGAFGAMAFTVGKYGIDSIGSLGLLILTFY
VACGVFLMVVIGTLARLHGFSLWKVLRYFREELLIVLGTSSSEPVLPRVLQKLEALGCKK
GVSGLVLPMGYSFNLDGTAIYLTLASLFIAQACDIHLSGGQIFAMLGVMLLTSKGAAGVT
GSGFVALVATLTVMPDLPVAGVALLVGIDRFMSEARALTSIISNCVASIVVSIWENACDR
EVLQRELNQSYASTERCLEEKGDIAVLPLNAPAQPSH