Protein Info for AZOBR_RS28100 in Azospirillum brasilense Sp245

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 PF00126: HTH_1" amino acids 6 to 64 (59 residues), 85.5 bits, see alignment E=1.8e-28 PF03466: LysR_substrate" amino acids 91 to 292 (202 residues), 171.7 bits, see alignment E=1.5e-54

Best Hits

Swiss-Prot: 50% identical to YBHD_ECOLI: Uncharacterized HTH-type transcriptional regulator YbhD (ybhD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 73% identity to bja:blr7098)

Predicted SEED Role

"LysR family transcriptional regulator YbhD" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AXW8 at UniProt or InterPro

Protein Sequence (296 amino acids)

>AZOBR_RS28100 LysR family transcriptional regulator (Azospirillum brasilense Sp245)
MNFELVDLKAFVAVAELGSFNRAAELLNLSQPALSRRIQKLEDTLGVALFERSTRHVALT
MVGRDFMPKVRRFLDEFESSLLGISDLGARSGGQITIASVPTAVFYFLPNAISRFSVAFP
RIRIRILDLGANEGLEAVARGEADFGINFIGTSHPDIEFTPLAEDPFVVACRHDHPLAAR
REVGWDELAAHRVITVGRTSGNRALIDNALAQHGLKLNWSYEITHLASSLGLVEAGLGVA
VLPKLATPASGHPIIRTIPLSHPKISRTIGVVRRHGAILSPMAARFLEVLLGSWKA