Protein Info for AZOBR_RS26810 in Azospirillum brasilense Sp245

Annotation: quinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 PF08240: ADH_N" amino acids 28 to 89 (62 residues), 36.8 bits, see alignment E=4.5e-13 PF00107: ADH_zinc_N" amino acids 153 to 258 (106 residues), 97.7 bits, see alignment E=7.9e-32 PF13602: ADH_zinc_N_2" amino acids 186 to 324 (139 residues), 78.6 bits, see alignment E=1.3e-25

Best Hits

Swiss-Prot: 48% identical to CAA43_BURSP: 2-haloacrylate reductase (caa43) from Burkholderia sp.

KEGG orthology group: K00344, NADPH2:quinone reductase [EC: 1.6.5.5] (inferred from 62% identity to azo:azo3209)

MetaCyc: 48% identical to 2-haloacrylate reductase (Burkholderia sp. WS)
RXN-14536 [EC: 1.3.1.103]

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.3.1.103 or 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AX21 at UniProt or InterPro

Protein Sequence (326 amino acids)

>AZOBR_RS26810 quinone oxidoreductase (Azospirillum brasilense Sp245)
MVHAIRVHQPGGPEALVWEEVAVPPPGPGEALVRHTAIGVNLIDTYHRSALSGQYAIPRP
AVLGVEGAGVVEAVGPGVTDVAPGDRVAYWMLLGAYAERRIVPTHRLVKLPDTVSDEVAA
AAMVKGTTAQYLLHRVHPVKAGETLLVHAAAGGVGQMLCQWAHALGATVIGTVGSPEKAA
VARCAGCDHVILYREEDFAARVRDITDGRGVDVVYDSVGQDTFMASLDCLKPFGLMVSFG
QASGPVPPLDISMLAQKGSIFLAKPTLATVTRSRDDIETLAGGLFEALASGRVQVGIAHR
APLTDAASVHRDLEARRTTGSIVLIP