Protein Info for AZOBR_RS20085 in Azospirillum brasilense Sp245

Annotation: chemotaxis protein CheW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 PF01584: CheW" amino acids 26 to 159 (134 residues), 113.2 bits, see alignment E=3.7e-37

Best Hits

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 91% identity to azl:AZL_d03040)

Predicted SEED Role

"Positive regulator of CheA protein activity (CheW)" in subsystem Bacterial Chemotaxis or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8ANM8 at UniProt or InterPro

Protein Sequence (166 amino acids)

>AZOBR_RS20085 chemotaxis protein CheW (Azospirillum brasilense Sp245)
MSNAKLPATTKKSKGDEITSGGSQDYVTMTIADQLFGIPVLQVQDVLGHQRITRIPLAPP
EVAGSLNLRGRIVTAIDVRLRLGLTSRPKDKPGMSIVVDLRGELYSLMVDSVGEVLSLSN
DDFERNPATLDPRWREVSTGIYRLNGQLMVVLDVPRLLNFTTMEAA