Protein Info for AZOBR_RS20080 in Azospirillum brasilense Sp245

Annotation: ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 921 PF01627: Hpt" amino acids 3 to 95 (93 residues), 60.8 bits, see alignment E=3e-20 PF02895: H-kinase_dim" amino acids 239 to 298 (60 residues), 57.4 bits, see alignment 4.2e-19 PF02518: HATPase_c" amino acids 346 to 485 (140 residues), 63.1 bits, see alignment E=8e-21 PF01584: CheW" amino acids 491 to 624 (134 residues), 89.8 bits, see alignment E=3.2e-29 amino acids 653 to 739 (87 residues), 24.4 bits, see alignment E=4.8e-09 PF00072: Response_reg" amino acids 798 to 909 (112 residues), 72.1 bits, see alignment E=1.1e-23

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 88% identity to azl:AZL_d03050)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8ANM7 at UniProt or InterPro

Protein Sequence (921 amino acids)

>AZOBR_RS20080 ATPase (Azospirillum brasilense Sp245)
MDDLLSEFLTETNENLSVLDVELVRLEQNPNNPELLSNIFRLVHTIKGTCGFLGLPRLEK
VAHASENVLGKFRDGELTINPEAVSLILQALDTIKSLLAVLEATEAEPPGDDLPLIERLN
LCAEGKLGAAAPAKPAAAPVPPPAPAVAAAEEVPVSSSGNLTLDELEAIWNATPGPTSTA
LAPVAAEPAEEPAPSHDLVVPDPDPVPAAAKMPAPAAEAASGAGAGGEAATKESAVAAQT
IRVNVDLLENLMTMVSELVLTRNQLLQILRSQKESEFAAPLQRLNHVTSELQEGVMKTRM
QPIGNAWAKLPRLVRDLSHELGKKIDLQMLGADTELDRQVLELIKDPLTHMVRNSADHGL
EVPADRVRSGKSETGRITLNAYHEGGHIIIEIQDDGKGLAIDRIKQKAIQNGMASEGELA
AMSDQQIIQFIMKPGFSTAAKVTNVSGRGVGMDVVKTNIEKIGGTIEIKSQQGKGSTFVI
KIPLTLAIVSALIVECAGERFAIPQISVVELVRAAADSEHTIERLKGTPVLRLRNRLLPL
VSLQELLRLDDQEGGEKKTDETFIVVTQVGTYTFGIMVDRVFDTEEIVVKPVAPILRHIE
MFSGNTILGDGSVIMILDPNGIASATGEMAMGEAASKETTSVQATRQEDKMALLLFRAGA
GAPKAVPLSLVARLEDVDLASVESSNGMPVVQYRGKLMPLVPIDPGFMIGQEGRQPVLVF
ADGDRSMGLIVDEIVDIVEERLVVQLTADRPGLMGSAIIAGKATDVIDAGFFLTQAYKDW
FGSSSTDAYEEEKALQRVLLVDDSPFFRNLLTPLLSVAGYDVTAVENANEALALCEAGED
FDVIVSDIEMPGMSGFDFAEAVRQGGTRWSGTPMVALSSHASPRDLDRGRQAGFTDYVAK
FDRDALLYALQQTLSEQKGAA