Protein Info for AZOBR_RS07430 in Azospirillum brasilense Sp245

Annotation: LexA family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 PF01726: LexA_DNA_bind" amino acids 2 to 63 (62 residues), 50.7 bits, see alignment E=1.2e-17 TIGR00498: repressor LexA" amino acids 2 to 231 (230 residues), 166.8 bits, see alignment E=2.4e-53 PF00717: Peptidase_S24" amino acids 111 to 226 (116 residues), 98 bits, see alignment E=2.9e-32

Best Hits

Swiss-Prot: 74% identical to LEXA_RHOCS: LexA repressor (lexA) from Rhodospirillum centenum (strain ATCC 51521 / SW)

KEGG orthology group: K01356, repressor LexA [EC: 3.4.21.88] (inferred from 85% identity to azl:AZL_016060)

Predicted SEED Role

"SOS-response repressor and protease LexA (EC 3.4.21.88)" in subsystem DNA repair, bacterial (EC 3.4.21.88)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AL01 at UniProt or InterPro

Protein Sequence (232 amino acids)

>AZOBR_RS07430 LexA family transcriptional regulator (Azospirillum brasilense Sp245)
MLTRKQHELLLFINERLGQGGVSPSFDEMKDALNLKSKSGIHRLITGLEERGFIRRLPHR
ARALEVLRLPEGLETARTRPPRAKFQPNVIKGDFSFAGREANPASESVQLPLYGRIAAGT
PIEALRDGSAFVDIPAAMLGMGDHYALEVAGDSMVEAGILDHDTVVIQRCDSAENGSIVV
ALVDDAEVTLKRLRRKGNTVALEPANAAYETRIFGADRVRVQGRLVGLVRKY