Protein Info for AZOBR_RS06535 in Azospirillum brasilense Sp245

Annotation: serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details TIGR02037: peptidase Do" amino acids 47 to 503 (457 residues), 538.7 bits, see alignment E=5.5e-166 PF00089: Trypsin" amino acids 111 to 273 (163 residues), 72 bits, see alignment E=1.6e-23 PF13365: Trypsin_2" amino acids 114 to 249 (136 residues), 123.7 bits, see alignment E=2.6e-39 PF00595: PDZ" amino acids 285 to 364 (80 residues), 38.7 bits, see alignment E=2.7e-13 amino acids 413 to 484 (72 residues), 28.1 bits, see alignment E=5.4e-10 PF13180: PDZ_2" amino acids 290 to 379 (90 residues), 59.3 bits, see alignment E=9.9e-20 amino acids 416 to 485 (70 residues), 31.6 bits, see alignment E=4.4e-11 PF17820: PDZ_6" amino acids 315 to 368 (54 residues), 37.3 bits, see alignment 4.9e-13 amino acids 439 to 484 (46 residues), 28.1 bits, see alignment 3.6e-10

Best Hits

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 80% identity to azl:AZL_013610)

Predicted SEED Role

"HtrA protease/chaperone protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AKF7 at UniProt or InterPro

Protein Sequence (509 amino acids)

>AZOBR_RS06535 serine protease (Azospirillum brasilense Sp245)
LNPNHPIHRAESGRRLRVVPLIAALLLGLSAAVGTPAMAQSRPAPTSFADLSEKLLPAVV
NISTSQAVPQRQQGARPEMPQFPPGSPFEEFFRDFFDRQQQDQPQQPRKSTSLGSGFIID
AKNGYVVTNNHVIQDADEITVILQDDTNIKAELIGKDPKTDVALLKITTSHPLVAVPFGD
SDAMRVGDWVLAIGNPFGLGGSVTAGIISARQRDINAGPYDDFLQTDASINRGNSGGPMF
NLNGEVIGINTAIFSPSGGSVGIGFAIPSNLAKQVVAQLREYGKTRRGWLGVRIQGVTPE
IAESLGLQGHKGALVASITPNGPAAKAGIQAGDVVTKFDGKEINEMRRLPRVVAETPIDK
AVPIEVWRKGKSQQLQVKVGELEAAEESGLLAANPEEQRRQPQQAPAQKPTETLGLKLTN
ITPELRQQFEIKPELKGVVVTEVAGNSTASEKGIRAGDVIIEVGQEEVRKPEDVTSKIQK
AKEQGKKSILLLVDRHGDLRFVAIPLSQG