Protein Info for AZOBR_RS04785 in Azospirillum brasilense Sp245

Annotation: ATPase AAA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 644 PF01590: GAF" amino acids 80 to 201 (122 residues), 32.4 bits, see alignment E=3e-11 PF00158: Sigma54_activat" amino acids 333 to 496 (164 residues), 222.7 bits, see alignment E=5.8e-70 PF14532: Sigma54_activ_2" amino acids 338 to 504 (167 residues), 68.1 bits, see alignment E=2.4e-22 PF07728: AAA_5" amino acids 356 to 475 (120 residues), 23.5 bits, see alignment E=1.2e-08 PF02954: HTH_8" amino acids 602 to 635 (34 residues), 24.1 bits, see alignment (E = 6.2e-09)

Best Hits

Swiss-Prot: 57% identical to ACOR_CUPNH: Acetoin catabolism regulatory protein (acoR) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: None (inferred from 81% identity to azl:AZL_020640)

Predicted SEED Role

"Transcriptional activator of acetoin dehydrogenase operon AcoR" in subsystem Acetoin, butanediol metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AJ96 at UniProt or InterPro

Protein Sequence (644 amino acids)

>AZOBR_RS04785 ATPase AAA (Azospirillum brasilense Sp245)
MENAKAAHINELVRVSEGIASKRDAIITASWRRCVADHKLDPTVRREAYILPHERLCLHR
DAMDEFLRMARFGLEALYHQVAGMGYALLLTDSNGVTVDFIGDRASDDDLRRTGLYLGAD
WNEGRAGTCAVGTCIATGEALTVHQTDHFDATHIPLTCTAAPVFHSGGGLAAVLDISALR
SPEPKISQYLALQLVKAYTHKIENANLYNNFRREWVVKLSASQEFAEVDPDFVMALDGAG
RIIGFNHRAWQLLAGEGEGREDLIGRSFSDLFDCQVDDLVRFVRSLPTDQRTLHLRRSGT
PLFAQAMPPPAIAVPRPRKEDEGNLPKPLQAMCGDDPALKAVLTRAAKLVNTRMSLLIHG
ETGTGKEHLAKALHQSSVRAAKPFVAVNCAALPEALIESELFGYEPGSFTGATSRGKKGL
ILEADGGTLFLDEIGDMPLSSQTRLLRVLAEREVTPIGRTKAVSVDVRVIAATHRDLVEL
IKAGTFRDDLYFRLNGAVFTVPPLRQRGDLDWLIDRLLAERAERDGIGYTIAAPALAALR
AHGWPGNVRELVNALDYACAVCTDGLIELMDIPDPVQRSGVFEAWPASAPTPAPDSADPA
VRLREVLRRLHWNVSAAARDMGVDRSTIHRQMRRFGIVPPHRLD