Protein Info for AO356_13725 in Pseudomonas fluorescens FW300-N2C3

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 707 PF00072: Response_reg" amino acids 16 to 127 (112 residues), 94.1 bits, see alignment E=2.1e-30 PF00989: PAS" amino acids 155 to 262 (108 residues), 40.8 bits, see alignment E=6.9e-14 TIGR00229: PAS domain S-box protein" amino acids 155 to 263 (109 residues), 33.9 bits, see alignment E=3e-12 PF08448: PAS_4" amino acids 158 to 263 (106 residues), 33.9 bits, see alignment E=1.1e-11 PF13426: PAS_9" amino acids 163 to 263 (101 residues), 34 bits, see alignment E=1e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 272 to 434 (163 residues), 138.8 bits, see alignment E=1.4e-44 PF00990: GGDEF" amino acids 276 to 432 (157 residues), 143.4 bits, see alignment E=1.9e-45 PF00563: EAL" amino acids 452 to 687 (236 residues), 233.6 bits, see alignment E=7.5e-73

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a5259)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9W8B3 at UniProt or InterPro

Protein Sequence (707 amino acids)

>AO356_13725 diguanylate cyclase (Pseudomonas fluorescens FW300-N2C3)
MECAQPTPGEDSSVLLIVDDYPENLLSMRALLQRQDWQVMTASSGVEALNLLLEHDIDLV
LLDVQMPEMDGFEVARLMRGSQRTRLTPIIFLTANEQSQDAVIKGYASGAVDYLFKPFDP
QILKPKVQALLEHQRNRRALQRLSQDLEAARAFNASVLDNAAEGILVVDENGCIRFANPS
TCRLLNATADQLQGMPFLDFLQKPHIPEWADSDIHNAYRRGETWRLHDAVLRTAPGQQVS
VALSCAPLPSEQKAMVVTLQDMSVVRHLHQQLEYQAVTDPLTGLLNRRGFYQTAENLLMR
SERLESNWVLLYLDLDGFKRVNDSLGHDAGDRVLRWVSEQLKACLRPFDILARLGGDEFT
ALLDLEFPEQAAKIAEKLIERVAICQQIEGMDVALGASIGIATYPDCGANLDGLLRASDI
AMYEAKRAGRQQYRFYDHEMNGRARSRLMLEESVRSAIENRDFNMVYQPQVSIVDGRIRG
FEALLRWQHPSVGDVPPGLFLPLLEEARLISRLGSWIYHRSAAQRKVWERLFADDLVLGV
SLSSTQFGMPNLVTELRQVLERHALKPRQLEVEVTEDALMRNPDETQKQLRLLRQLGVRV
ALDDFGSGPCSLTHLRDLDLDTLKLDRHLIARLPGSPRDAALAASVIDLCTQLGLRVIAE
GVETREQYLWLHAHGCEFVQGFLVARPLMAEDTDVFATPFDWSAVQA