Protein Info for AO356_03195 in Pseudomonas fluorescens FW300-N2C3

Annotation: 2-dehydropantoate 2-reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details TIGR00745: 2-dehydropantoate 2-reductase" amino acids 8 to 315 (308 residues), 246.9 bits, see alignment E=1.4e-77 PF02558: ApbA" amino acids 9 to 158 (150 residues), 127 bits, see alignment E=4.9e-41 PF08546: ApbA_C" amino acids 191 to 311 (121 residues), 113.2 bits, see alignment E=1.1e-36

Best Hits

KEGG orthology group: K00077, 2-dehydropantoate 2-reductase [EC: 1.1.1.169] (inferred from 95% identity to pba:PSEBR_a1608)

Predicted SEED Role

"2-dehydropantoate 2-reductase (EC 1.1.1.169)" in subsystem Coenzyme A Biosynthesis (EC 1.1.1.169)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.169

Use Curated BLAST to search for 1.1.1.169

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WDC9 at UniProt or InterPro

Protein Sequence (317 amino acids)

>AO356_03195 2-dehydropantoate 2-reductase (Pseudomonas fluorescens FW300-N2C3)
MQAGVKPRIGMIGTGAIGGFYGVMLARAGFDVHFLLRSEFAAVAEAGLRIDSAVHGTLAL
DPVQAYRSAADMPPCDWLLVGAKTTSNADLAPAIAQAAADGAKVLLLQNGLDVEDDLRPL
LPDSLHLLGGLCLICVHRVGPGVIAHQALGAVNVGYHSGPCADQAQRMAIVEEATTVFRC
AGIEAQAMPGLQQARWQKLVWNVPYNGLSVLLGASTTPLMANSHSRELIQALMAEVVRGA
QACGHHIAPGYAEYLFTMTEKMPDYWPSMYHDYSHKRALELDAIYGRPLAAAKAAGCELP
KIEALYQALAFMDRCNR