Protein Info for AO353_18490 in Pseudomonas fluorescens FW300-N2E3

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 151 to 175 (25 residues), see Phobius details PF00672: HAMP" amino acids 172 to 225 (54 residues), 29.9 bits, see alignment 1.1e-10 PF00512: HisKA" amino acids 231 to 293 (63 residues), 49.6 bits, see alignment E=6.7e-17 PF02518: HATPase_c" amino acids 339 to 443 (105 residues), 77.5 bits, see alignment E=2.1e-25

Best Hits

KEGG orthology group: None (inferred from 86% identity to pfo:Pfl01_1481)

Predicted SEED Role

"Putative two-component system sensor kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WID5 at UniProt or InterPro

Protein Sequence (448 amino acids)

>AO353_18490 histidine kinase (Pseudomonas fluorescens FW300-N2E3)
VRSLFWRILASFWLAIALVAGLSILLGHMLNQDAWILSRHPGLNTLAQEWTQLYEEKGED
AAQALLEQRKRRYHIDVQVLNEGGDPVVRGTFPRRAAALEARQNDNPDDSGRHLPWRRLT
VEYTSPKSAETYLLIYRIPHPELNAWHRNSLLWPFSALAIALVVLTLFSLLVTLSITRPL
SRLRGAVHDLGQTTYQQNSLARLANRRDEFGVLANDFNRMGARLQSLIGSQRQLLRDVSH
ELRSPLARLRIALALAERAGPEERGKLWPRLTRECDRLEALISEILVLARVDADNASAEA
VDLNALLNTVQKDAQLGAPEQSIRIEAERQLSLKGWPTMIERALDNLLRNAQRFNPAGQP
IEVLALRQGDRIVISVRDHGPGVEAEHLKQLGEPFFRAPGQTAPGHGLGLAIARRAAERH
GGSLILANHPEGGFIASLELPLEPGIAP