Protein Info for AO353_17495 in Pseudomonas fluorescens FW300-N2E3

Annotation: cytochrome C oxidase subunit III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 transmembrane" amino acids 41 to 60 (20 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 153 to 172 (20 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details PF00510: COX3" amino acids 37 to 211 (175 residues), 33 bits, see alignment E=3e-12

Best Hits

Predicted SEED Role

"Alternative cytochrome c oxidase polypeptide CoxO (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VVZ9 at UniProt or InterPro

Protein Sequence (230 amino acids)

>AO353_17495 cytochrome C oxidase subunit III (Pseudomonas fluorescens FW300-N2E3)
MNRLLLRNVDGADPGGSWSGGPEDIQAAEAANRIQNARVGLRLFLAVVSSLFFLFLVAFI
ERSQMADWQPLTEPLAPLANLWQLWLNTAFLVFSCIALQWSRMAARQGRLDATVIGFAVG
GIFAAAFLTGQLWVWQQFVAWGYFVASNPANSFFYLLTGLHGFHLLGGLIAWSRTVAKFL
HHVPLPQLSASVELCAIYWHYLLGLWFVLFALLTSTPATYEAIARFCGLR