Protein Info for AO353_13770 in Pseudomonas fluorescens FW300-N2E3

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 921 TIGR00229: PAS domain S-box protein" amino acids 431 to 553 (123 residues), 26.2 bits, see alignment E=3.6e-10 PF08447: PAS_3" amino acids 458 to 539 (82 residues), 46.5 bits, see alignment E=8.9e-16 PF08448: PAS_4" amino acids 566 to 675 (110 residues), 28.5 bits, see alignment E=3.9e-10 PF00512: HisKA" amino acids 689 to 755 (67 residues), 27.8 bits, see alignment 5.4e-10 PF02518: HATPase_c" amino acids 801 to 913 (113 residues), 67.4 bits, see alignment E=3.8e-22

Best Hits

KEGG orthology group: None (inferred from 76% identity to pfl:PFL_0687)

Predicted SEED Role

"Sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9W6A0 at UniProt or InterPro

Protein Sequence (921 amino acids)

>AO353_13770 histidine kinase (Pseudomonas fluorescens FW300-N2E3)
LTPGEKLFGRLLNRPPFQEPDTPYSLVTQNVGLHLLLNPQGRVLKMSGPLRHALAQRPHA
DQPPHLIDYLLPHSHLVVEGIPAEWQGQNLDLDFAGLGGQTLHLRGWVQPTPDSWLLQLL
DIGDLLHERQQAHSREECQSFAGHMSEQLRLCSLMRLPEVLTEQLQGLAQRWHIPCVAIA
LLDDQEQGWLIHSQYNAHDAPQLWQTGQPLGTSLDSLSGNTPLRLSVAHGFSEHPRLQGT
FGNTDGFLVPYRDDHGVAAWLLCGFYPVQQRAPQLSERDWSLLAAALAGPLLGRLREQHQ
HHQLERLEALQGLLGTGWWELFGNIDEVQLAPQLAFTLHLESARLPLAQWLTLIHPADRQ
ELASRVQDLQQHGKTLLLCVRLHRADDAQTPVWYRLQGQALGVGEQRRLVGFMLDISDIK
NQQQQAAAAHARLDNLIASSPAVIYVQRYVEGALQPSFFSASLLPLLGWNLNDLAGNALV
ERVHPEDRDLYFERTRQLLREGSVRARYRLRDQRGDYHWLLDEARLLRDDLGLPVEAVGL
WLDVSEATQAAEQVKQSEERYRILVEDSPAMICRYRPDLTLTFGNRPLATYLECTPEQLP
GVDLGSWLSAEQREAFVLRLRQLTPEFPVSTAEISLQLPGRENAWWVWSDRGVFDERGRL
IEIQAVGRDNTEVRRSQQQLTQSAKMATLGEMATGLAHEINQPLNVMRMAIVNVLKRLSN
GDVQIDYLQDKLKRIDAQVQRAARVVDHMRVFGRRSEIEQQLFNPAHAVEGTLSLLAEGM
RGKGVDLRISEFGFEANVRGHVDQLEQVLINLMVNARDALLSKRESDPAFKPWISLYAER
DHSSLRLWVEDNAGGIDPRLLERIFEPFFTTKPVGVGTGLGLSVSYGIVENMGGRLSVRN
SIEGARFCIELPIALGDQITR