Protein Info for AO353_03445 in Pseudomonas fluorescens FW300-N2E3

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF07660: STN" amino acids 69 to 118 (50 residues), 36.3 bits, see alignment 7.9e-13 TIGR01785: TonB-dependent heme/hemoglobin receptor family protein" amino acids 127 to 849 (723 residues), 409.4 bits, see alignment E=3e-126 TIGR01786: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein" amino acids 129 to 850 (722 residues), 530.5 bits, see alignment E=7.1e-163 PF07715: Plug" amino acids 142 to 251 (110 residues), 100.5 bits, see alignment E=1.5e-32 PF00593: TonB_dep_Rec" amino acids 342 to 808 (467 residues), 237.9 bits, see alignment E=8.4e-74 PF14905: OMP_b-brl_3" amino acids 521 to 817 (297 residues), 39.4 bits, see alignment E=8.5e-14

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 82% identity to pfo:Pfl01_4379)

Predicted SEED Role

"TonB-dependent hemin , ferrichrome receptor" in subsystem Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9W7G2 at UniProt or InterPro

Protein Sequence (854 amino acids)

>AO353_03445 TonB-dependent receptor (Pseudomonas fluorescens FW300-N2E3)
MSSRLTRRSSSPSCVLSLLTAAILLAGTAQVSAATVEQPSRNMGDYSFAIAQQPLVSALN
AFTAVTGWQVGLPAELAEGVASPGVHGSLPPDKALDRLLVGTNLRYRKLGNHNIVLEKRN
VDGTLALQQMTISATRQEQSVDSVPSTVTVHTREELDHDNVNTIKELVRYEPGVSVGGTG
TRGGISGYNIRGIDGDRVLTQVDGVEVPNGFFNGPYAKTQRNYVDPEIIKRVEILRGPAS
VLYGSNAIGGAVSYFTLDPNDIIKPGKDVGARLKTGYNSADDSWLKSASVAGRAEQFDGL
LHFSQRDGHETESFGSNNGTGLNRTAANPEDVRTTNVLAKAGWNYADDARLGLTYEKYKD
DRDTDQRSAVGGPFNNGQPMGMYRSRTGNDTITRERFGLENSFALDSLLVDHLKWSLNYQ
IAKTDQSTLENYFPFSRNVMRSRETLYEEKQWVFDAQLDKAFNIGETDHLLTYGTTIKQE
KVSGSRSGSGTCLAVGRGCTAIGATSPSDVLKKSSDFPDPTINTYSLFAQDQIRWNKWTF
LPGLRYDYTRLKPHITQEFLNTVAADGKGSVSDENKTWHRVSPKFGLTYALTDNYTWYGQ
YAEGFRTPTAKALYGRFENTTTGYRVEPNPNLGPEKSQSYETGLRGNFESGHFDVAVFYN
KYRDFINEDAVTPGYNELTFQSNNIKRATIKGVELKGRLNLDTFGAPQGLYTRGSVAYAH
GRNNDTGEPLNAVNPLTGVFGLGYDQDNYGALLSWTLVQKKNLVDSSSFKSPDGVSSQFK
TPGYGVVDLSGFYKVTDDVTVSAGVYNLADKKYWQWDNVRGYDSVGEAAVISPANLDRLT
EPGRNFAINLIWDI