Protein Info for ABZR87_RS22855 in Ralstonia sp. UNC404CL21Col

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 33 to 54 (22 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 149 to 169 (21 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 221 to 379 (159 residues), 139.8 bits, see alignment E=3.5e-45 PF00990: GGDEF" amino acids 221 to 377 (157 residues), 135.5 bits, see alignment E=7.2e-44

Best Hits

KEGG orthology group: None (inferred from 65% identity to bvi:Bcep1808_3810)

Predicted SEED Role

"diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (390 amino acids)

>ABZR87_RS22855 GGDEF domain-containing protein (Ralstonia sp. UNC404CL21Col)
MLDPGVAIATSALMSFVLLGLLGSLLRAGKPGIAEWFGANLAVVLALPLILLRGNIPDSL
SVVVANVLLALGGAAYYAGCARFLGRRPQWPILLAGVAAVGVAVIYWRYAVDSIPMRVFS
TTLFSAAFCTALVWMLLRHSPAGRSTYPYRVTAVIAFVFGVCQLVRGIYFLTLDAASSPT
MFATAGSVLLLVVAAAIMPILSMSAMLMVHDALLADACDAANRDFLTGALSRQGFEALAR
RHVGRVQHHARPLALLILDLDHFKRINDTLGHAAGDAVLRAFVQMAHAQLRPTDVLGRIG
GEEFALLLPDTDSSNATHLAERLRKAAAAQVVAAGAQSCCYSISGGVAAWQPGESFDRLS
ARADRALYDAKHQGRNRICPADVVNVVAMA