Protein Info for ABZR87_RS21475 in Ralstonia sp. UNC404CL21Col

Annotation: efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1049 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 344 to 364 (21 residues), see Phobius details amino acids 371 to 388 (18 residues), see Phobius details amino acids 399 to 418 (20 residues), see Phobius details amino acids 438 to 462 (25 residues), see Phobius details amino acids 476 to 501 (26 residues), see Phobius details amino acids 555 to 577 (23 residues), see Phobius details amino acids 888 to 907 (20 residues), see Phobius details amino acids 914 to 934 (21 residues), see Phobius details amino acids 944 to 965 (22 residues), see Phobius details amino acids 988 to 1005 (18 residues), see Phobius details amino acids 1017 to 1040 (24 residues), see Phobius details TIGR00914: heavy metal efflux pump, CzcA family" amino acids 1 to 1045 (1045 residues), 1099.1 bits, see alignment E=0 PF00873: ACR_tran" amino acids 7 to 1043 (1037 residues), 946.2 bits, see alignment E=1.1e-288

Best Hits

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1049 amino acids)

>ABZR87_RS21475 efflux RND transporter permease subunit (Ralstonia sp. UNC404CL21Col)
MIDALIRGALKQRLVVAVIAAVLLFFGLDAARKLSLDAFPDVTNVQVQIATEAPGRSPEE
VERFVTVPVEMAMTGLPALTEMRSLNKPGLSLITLVFTDETDVYFARQLVMERLIEVQSR
MPTGVTPVLGPVSTGLGEVYQYTLDKPDDGDKELSVEELTQRRIAQDWVVRPLLRSIPGV
AEINSQGGYEKQYQVLVNPERLRHHNVTVKQVFEALAANNANSGGGVLPHFAEQYLIRGV
GLVRDTNDIGAIVLKEVNGTPLTIRDVADVKIGTAVRAGAVVKNGVTESVGGVVMMMRGG
NAKEVVARIQDRVKAINNDGMLPDGLKIVPYYERSELVDSALQTVIKVLAEGVVLVVIVL
LLFLGDIRSSLIVVGTLILTPLLTFMAMNKLGISANLMSLGGLAIAIGLMVDGSVVVVEN
AFAHLAKPRDPNESRARVILHAVTEVATPVIFGVGIIILVFLPLMTLEGMEGKMFAPLAF
TIAIALFFSLVLSLTLTPVLSSYLLKPKVHKHVEGEHSDDPHAEHDAHDTWLIRKMKKPY
LRLLELSLNNGRKTVIVAVAVFLATGALMPFLGTAFIPEMKEGSVVPGINRAPNISLEES
IRMEMEAMRLVMQVPGVKSAVSGVGRGESPADPQGQNESTPIVSLKPRDAWPKGWNQDDI
AEAMRKALQVLPGVQIVMAQPISDRVDEMVTGVRSDVAIKVFGDDLNTLREKAEAIAKVA
QGIQGAQDMRVERITGQQYLQIAIDRQAIARHGLNAADVHNVIETAIGGKEATEIFEGER
RFSAVVRLPDAYRGSVEAIRNLIVAAPNGAQVPMESIARIDVTDGPAQISRELGKRRVVV
GVNVRDRDLGGFVAELQAAVAQKVKLPEGYYLEWGGQFQNMERAMGHLKVIVPITVAAIF
FLLFLLFNSVRYATLIILVLPFASVGGIIGLFVTGEYLSVPASVGFVALWGIAVLNGVVL
VSTIRSLREQGMSVEESVRLGSRMRFRPVMMTATVAMLGLIPFLFATGPGSEVQRPLAIV
VIGGLLTCTLLTLVMLPTLYKWFDEESKA