Protein Info for ABZR87_RS19500 in Ralstonia sp. UNC404CL21Col

Annotation: ShlB/FhaC/HecB family hemolysin secretion/activation protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF08479: POTRA_2" amino acids 70 to 144 (75 residues), 67.7 bits, see alignment E=6.6e-23 PF03865: ShlB" amino acids 259 to 522 (264 residues), 36 bits, see alignment E=6e-13

Best Hits

KEGG orthology group: None (inferred from 96% identity to rpi:Rpic_4241)

Predicted SEED Role

"Probable activation/secretion signal peptide protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>ABZR87_RS19500 ShlB/FhaC/HecB family hemolysin secretion/activation protein (Ralstonia sp. UNC404CL21Col)
MRTTTMRLALATGVALTGPALSWAQSSPTQGNPIDTLPKVDTSRPPQQKIQVEVQRPNPA
LENLLATHLTPTKFQIEGVKTLPFPEVAAYFAPLAGHDITVAQLLQAANEVTKLYADRGF
PLSFAFVPAQTFEGGVVRVTVVEGYVARMRIEGTPGPLEGRLRDISQRLMNEKPLRRETF
ERVTGVLALQPGVQITATVQPPTTTDGASELVLNVKRQPYTIGTGVEYRSPGVRAIITGT
LNSVTPLGEQITVSTLQPRGSDHETFYSATWAQPIGTDGLLAKLTWSHYRGMPENLPLEQ
LGYQSRYLTDTQRLGLSLSYPVLLSNTRNLTLTGTFYGNDDKQRYTPQNPGFAQTELDTK
VRVAGAEVLYTEVNPGETRRASLGLYQGINSLGAGKGASANANNNVDLSFLRTRITASEA
HDLPLGFGVVVSGAAQYSGAVLPSSEQISFGGRFFGLAYPAGEVAGDRGWGASVEINRAF
QVSMDYLKTVQPYVLYDTAKVYSNAGTLVHDQLGSIALGVRFSDRKYYTLDLAIARPVGD
KPINSSSRSLRFNAAYTYQFN