Protein Info for ABZR87_RS16535 in Ralstonia sp. UNC404CL21Col

Annotation: SDR family NAD(P)-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 PF00106: adh_short" amino acids 11 to 198 (188 residues), 205.7 bits, see alignment E=1e-64 PF08659: KR" amino acids 13 to 163 (151 residues), 56 bits, see alignment E=1e-18 PF01370: Epimerase" amino acids 13 to 252 (240 residues), 24 bits, see alignment E=4.8e-09 PF13561: adh_short_C2" amino acids 16 to 257 (242 residues), 208 bits, see alignment E=3.4e-65

Best Hits

Swiss-Prot: 35% identical to LVR_LEIAQ: Levodione reductase (lvr) from Leifsonia aquatica

KEGG orthology group: None (inferred from 97% identity to rpf:Rpic12D_3945)

MetaCyc: 35% identical to levodione reductase monomer (Leifsonia aquatica)
1.1.1.M48 [EC: 1.1.1.M48]

Predicted SEED Role

"D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30)" in subsystem Polyhydroxybutyrate metabolism (EC 1.1.1.30)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.30

Use Curated BLAST to search for 1.1.1.30 or 1.1.1.M48

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (260 amino acids)

>ABZR87_RS16535 SDR family NAD(P)-dependent oxidoreductase (Ralstonia sp. UNC404CL21Col)
MATPAMLSGHHAVVTGAGRGIGAAIAAQLAAHGATLTLMGRNADVLHATAKTLPDSARAQ
VVTCDVTDEASVSGAFESARAGLGPISILVNNAGQAESAPFAKTTLDQWQRMLAVNLTGT
FLCTQAALADVQASGRGRIVNIASTAGQRGYAYVSAYVAAKHGVIGLTRSLALELAARGV
TVNAVCPGYTETDIVRESIDRIVARTGRSAEEARAELVKGNPQGRLIAPDEVANAVVWLC
SEGASSITGQAISVSGGEVM