Protein Info for ABZR87_RS12255 in Ralstonia sp. UNC404CL21Col

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 792 PF01315: Ald_Xan_dh_C" amino acids 26 to 145 (120 residues), 100.9 bits, see alignment E=7.7e-33 PF02738: MoCoBD_1" amino acids 161 to 410 (250 residues), 265.5 bits, see alignment E=5.3e-83 PF20256: MoCoBD_2" amino acids 436 to 724 (289 residues), 326.3 bits, see alignment E=2.9e-101

Best Hits

KEGG orthology group: None (inferred from 99% identity to rpi:Rpic_1353)

Predicted SEED Role

"Carbon-monoxide dehydrogenase form II, large subunit (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (792 amino acids)

>ABZR87_RS12255 xanthine dehydrogenase family protein molybdopterin-binding subunit (Ralstonia sp. UNC404CL21Col)
MNAPAEPNNHLIGAAVKRKEDFRFLTGAGQYTDDVVQAHQSYAVFLRSPYAHARIKHINA
EAARNHPGVLAVLTGDDLAADKVNGLPCGWLIHSIDGTPMKEPPHPVLAQGKVRHVGDQV
ALVVAESVKIAKDAVEMIDVEYDELRAVVDTATADTAGTAVHDDVPNNTCYTWGHGDKAA
TDAAFAKAAHVTQLDIVNNRLIPNAIEPRAVNASYSRQDDSYTLYVANQNPHVERLLMSA
FVLGLTEAKVRVIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAH
GRDHVTHAELALDAQGNFLAMRVHTTANMGAYLSTFASSVPTILYATLLAGQYKTPAIYA
EVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAARELQIDPAELRRRNFIRTFPYATPV
GLTYDTGDYEPCLDRAIELADVKGFAARRDASRAKGRLRGMGYSCYIEACGLAPSNIAGA
LGARAGLFEAGEIRVHPTGSVTVFTGSHSHGQGHETTFAQVVADRLGVPIDNIEIVHGDT
GRIPFGMGTYGSRSIAVGGSAIMKALDKIEAKAKKIAAHLLEASAEDIEFKDGVFRVAGT
DRTKTFGEVALTAYVPHNYPLDKLEPGLDENAFYDPTNFTYPAGAYICEVEVDPDTGEVH
IDRFVAVDDFGNIINPMIVEGQVHGGLGQGIGQALLEACVYDENGQLLTGSYMDYAMPRA
NDLPSFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPALINAIVDALAPLGVKDIQMPATP
HRVWQTIQAAKA