Protein Info for ABZR87_RS12080 in Ralstonia sp. UNC404CL21Col

Annotation: pca operon transcription factor PcaQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 TIGR02424: pca operon transcription factor PcaQ" amino acids 11 to 311 (301 residues), 317.2 bits, see alignment E=4.2e-99 PF00126: HTH_1" amino acids 15 to 74 (60 residues), 72.5 bits, see alignment E=2.1e-24 PF03466: LysR_substrate" amino acids 103 to 309 (207 residues), 121.9 bits, see alignment E=2.6e-39

Best Hits

Swiss-Prot: 49% identical to YDCI_ECOLI: Uncharacterized HTH-type transcriptional regulator YdcI (ydcI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to rpf:Rpic12D_1381)

Predicted SEED Role

"Pca operon transcriptional activator PcaQ"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>ABZR87_RS12080 pca operon transcription factor PcaQ (Ralstonia sp. UNC404CL21Col)
MESAFSADLPSRIRFRHLSCFVAIAQERNLRRAAERLHLSQPAVSKTLGELEALAGVQLV
ERGRQGARLTAAGEQFLRHAVGVTQALESATAALMGSTDASAPVVHVGALPTVASSLLPQ
AIAHLHAQRPHAGVRLRTGTNVELLTALKAGELDFIVGRMAEPDRMQGLSFELLYAEPLA
LVVRPGHPLLTQAGASASLQAVLDYPLVIATPGTVPRHHTEALFQTHGLRLPAGVTETLS
VSVARLLACRSDAVWITPERAAGDDLAHGQLARLDIVTSGTKEPVGLLRRSAATPSELAS
AFMELLTELAQTPG