Protein Info for ABZR87_RS11690 in Ralstonia sp. UNC404CL21Col

Annotation: ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 645 PF00005: ABC_tran" amino acids 19 to 178 (160 residues), 80.4 bits, see alignment E=6.9e-26 amino acids 334 to 465 (132 residues), 81.6 bits, see alignment E=2.9e-26 PF12848: ABC_tran_Xtn" amino acids 217 to 293 (77 residues), 98.7 bits, see alignment E=5.6e-32 PF16326: ABC_tran_CTD" amino acids 574 to 639 (66 residues), 41.4 bits, see alignment E=4.7e-14

Best Hits

KEGG orthology group: K06158, ATP-binding cassette, sub-family F, member 3 (inferred from 99% identity to rpf:Rpic12D_1315)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ATP-binding protein" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (645 amino acids)

>ABZR87_RS11690 ATP-binding cassette domain-containing protein (Ralstonia sp. UNC404CL21Col)
MIRFDDLVLQRGTKVLFDHATATLNPGERVGLVGVNGSGKSTLFSMLRGELHADGGEVAI
PPTWQVAHVAQETPAVDRSALDYTLDGDTRLRDIERRLAAAEAAHDGHAQAEAHTAFADA
DGYTAPARAQALLLGLGFTMAQTTQPVASFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
DLDAVVWLEDWLSRYAGTLVMISHDREFLDGVCNVTLHIEHQKLKRYGGNYTQFETQRLQ
QMALQEASYARQQKQIAHLESFITRFKAKASKAKQAQSRVKALERMERLAPVHAAAGFSF
EFREPEAAPNPMLTFEGVDCGYPGPSVDEPITILKHLTFSIQTGQRIGLLGANGQGKSTL
VKTLAETLAPLSGTIRRGKGLQIGYFAQHQLETLDDHASPLLHLARLAPDVREQELRDFL
GSFNFRGDMATSPIEPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLDTREALTMALA
QFDGTLILVSHDRHLLRATTDQFLLVGQGTVAPFDGDLDDYRDWLLKQAAAKRAAAGAQA
ASADADGAPATNRRDQKREEAAERQRLNALRKPLQKNVDAIEKRMAPLQKEKAELEAFLA
DGAAYEEANKARMMESLRRQAELNAELDELEERWLELHEQLEQIN