Protein Info for ABZR87_RS10245 in Ralstonia sp. UNC404CL21Col

Annotation: excinuclease ABC subunit UvrC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 657 TIGR00194: excinuclease ABC subunit C" amino acids 32 to 308 (277 residues), 325.5 bits, see alignment E=3.5e-101 PF01541: GIY-YIG" amino acids 42 to 116 (75 residues), 33.5 bits, see alignment E=1.1e-11 PF02151: UVR" amino acids 227 to 259 (33 residues), 34.1 bits, see alignment (E = 4.3e-12) PF08459: UvrC_RNaseH_dom" amino acids 439 to 590 (152 residues), 156.2 bits, see alignment E=1.6e-49 PF14520: HHH_5" amino acids 605 to 656 (52 residues), 33.5 bits, see alignment 1.2e-11

Best Hits

Swiss-Prot: 90% identical to UVRC_RALSO: UvrABC system protein C (uvrC) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03703, excinuclease ABC subunit C (inferred from 97% identity to rpi:Rpic_0936)

Predicted SEED Role

"Excinuclease ABC subunit C" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (657 amino acids)

>ABZR87_RS10245 excinuclease ABC subunit UvrC (Ralstonia sp. UNC404CL21Col)
MSSDPTQPQPPETPDSVEPSAPANVPEFDAKAHIARLPNLPGVYRYFDAQGNVLYVGKAR
DLKKRVSSYFNKTLLSPRIAMMVAKIARIDTTVVRSEAEALLLENNLIKALAPRYNILFR
DDKSYPYLKLTHHAYPRMAYYRGATDRKHQYFGPFPSAHAVRESMQILQKVFQLRTCEDT
VFNNRTRPCLLHQIHRCSGPCVQAISPEDYARDVANAAGFLQGRQDEVMQTLQDKMQRYS
ESLAFEQAAIVRDQIGALSTVLKQQSVEEVGHASDIDILAVAIKGGHACVNLAMVRGGRH
LGDKAYFPTHVEEGAAIVGVDVEAGGDPAAETSRDAERMASDILEAFVAQHYLDQFVPPV
LVVSHQIHATELIDALAEQAGRRISVVRQPQGGRRAWLEMAEKGAELSLMRRLSEQGSQQ
ARTRALAETIGIDLEDLAALRVECFDISHTAGEATQASCVVFHSHAMQNSEYRRYNIQDI
TPGDDYAAMRQVLTRRYQKIVEQAGEDTPNMPSIVLIDGGKGQVEVARQVFEELGLDIGL
LVGVAKGEGRKVGLETLIFADGRPSLELGQGSAALMLVAQIRDEAHRFAITGMRAKRAKA
RNTSRLEEIEGIGAKRRQRLLARFGGLRGVMAASVDELATVEGISQTLAEEIYRQLH