Protein Info for ABZR87_RS09950 in Ralstonia sp. UNC404CL21Col

Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 PF00294: PfkB" amino acids 16 to 307 (292 residues), 248.9 bits, see alignment E=7.8e-78 TIGR02152: ribokinase" amino acids 17 to 312 (296 residues), 376.9 bits, see alignment E=3.6e-117 PF08543: Phos_pyr_kin" amino acids 192 to 291 (100 residues), 32.5 bits, see alignment E=6.2e-12

Best Hits

Swiss-Prot: 43% identical to RBSK_SCHPO: Ribokinase (rbk1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 94% identity to rpf:Rpic12D_0943)

MetaCyc: 37% identical to deoxyribokinase monomer (Salmonella enterica enterica serovar Typhi)
RXN-14223 [EC: 2.7.1.229]

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.15 or 2.7.1.229

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>ABZR87_RS09950 ribokinase (Ralstonia sp. UNC404CL21Col)
MVAKRPSASSAHPAADVLIVGSLNMDLVIRTPRLPRPGQTVAAPALETIPGGKGANQAVA
TARLGARVAMLGCVGDDAYGTALREGLRREGVDTSMVSVHAGAATGIACVTVANSGQNTI
VIVAGANELLTPAMIEAQQAAFERARVIVCQLESPPDAVECALKLGQRLGKTVILNPAPA
IGPLPTPWIAACDYLIPNETEAALLTARPVDSPEAALDAAADLHAQGARHVIVTLGARGV
AYVDAQSRLLMPAPIAHAIDTTAAGDTFVGALAVALAEGVSPDTAIEFGQAAAAVSVTRL
GAQPSIPFRSELGAPAAPATH