Protein Info for ABZR87_RS08315 in Ralstonia sp. UNC404CL21Col

Annotation: saccharopine dehydrogenase NADP-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 286 to 305 (20 residues), see Phobius details PF03435: Sacchrp_dh_NADP" amino acids 8 to 138 (131 residues), 59.4 bits, see alignment E=2.5e-20

Best Hits

KEGG orthology group: None (inferred from 96% identity to rpi:Rpic_0541)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>ABZR87_RS08315 saccharopine dehydrogenase NADP-binding domain-containing protein (Ralstonia sp. UNC404CL21Col)
MPAPDYDVVVFGATSFVGQILARYLAEHFSGDAETLRWAIAGRSEAKLQELKRSLGAAGG
SVPIIVADAANEAQLQALCAQTRVVVSTVGPYALYGEPLIKVCAESGTDYCDLTGETQWI
KRMIGKYEATAQQSGARIVHCCGFDSVPSDMGVYFLQQHAMQQWGTPATQVKLRVKTLKG
GASGGTIASLINVVQEAAADAALRKELADPYALCPKGHGFTARQRSVRGAAFDADFDAWI
APFVMAAINERVVHRSNALSGNAYGNRFLYDEAVITGHGLSGRMKAVTMVAGLGAFMLGI
VIKPARIVMQRFLLPKPGEGPTPAAQLAGRYDLRLFGRTDEGNTLRVKVTGDRDPGYGST
GKMLGQAAASLALDHVKDGIKTGRPGGFWTPATMFDERFIERLTRHAGLRFERI