Protein Info for ABZR87_RS07700 in Ralstonia sp. UNC404CL21Col

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 signal peptide" amino acids 1 to 46 (46 residues), see Phobius details PF09312: SurA_N" amino acids 91 to 208 (118 residues), 118.5 bits, see alignment E=5.7e-38 PF13623: SurA_N_2" amino acids 93 to 171 (79 residues), 29.6 bits, see alignment E=1.7e-10 PF13624: SurA_N_3" amino acids 93 to 207 (115 residues), 50.1 bits, see alignment E=8.7e-17 PF13616: Rotamase_3" amino acids 240 to 343 (104 residues), 72.7 bits, see alignment E=1.1e-23 amino acids 352 to 451 (100 residues), 87.3 bits, see alignment E=3.3e-28 PF00639: Rotamase" amino acids 247 to 339 (93 residues), 72.1 bits, see alignment E=1.9e-23 amino acids 360 to 450 (91 residues), 82.7 bits, see alignment E=9.4e-27 PF13145: Rotamase_2" amino acids 259 to 346 (88 residues), 30 bits, see alignment E=2.5e-10 amino acids 370 to 456 (87 residues), 30.8 bits, see alignment E=1.3e-10

Best Hits

Swiss-Prot: 83% identical to SURA_RALSO: Chaperone SurA (surA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 97% identity to rpi:Rpic_0392)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (500 amino acids)

>ABZR87_RS07700 peptidylprolyl isomerase (Ralstonia sp. UNC404CL21Col)
MNNDIMAFQSTAFATRVAPLGRLRVATGVLVALLAGTTLSTAVHAQQAPSAKKTAPVRGI
FANPGSSPSQPLLQGTLPEPTAPGAPRSQLVDEVVAVVNTDVITRRELLNRADLVERTFR
VQNRPLPPRADLLGEVLEQLILERVQAQTAKESGIRVSDADVDRAVESVAQRNNLSVPQL
KSKLKDAGMTYDKYRDDLRQEILLARLREREVDSKVQVYDGEIDNYLAQQGGGAAPAGEQ
QYNVAQILVPVAEGASDAEKAAARSKAESLLKQAQGGADFAKLARDNSGAQDASQGGELG
LRPIGRLPAVFANAVVDMKAGQVASQVVESPAGYHVIKLLEKRAPGTAIAAKVQQTQVRH
ILIKTGPTMSADDARRQLTGLRDRIVHGYDFGDAARRYSQDGSAGAGGELGWVSPGQLVP
EFEQAMNQLKPGDVSQPVQSQFGVHLIQVEGRREAEVSGDRQRDYARSVIREQKVQAAYE
DWLRELRDSAHVEYRVNRQQ