Protein Info for ABZR87_RS05360 in Ralstonia sp. UNC404CL21Col

Annotation: membrane protein insertase YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 364 to 384 (21 residues), see Phobius details amino acids 428 to 450 (23 residues), see Phobius details amino acids 474 to 491 (18 residues), see Phobius details amino acids 503 to 527 (25 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 362 (359 residues), 361.7 bits, see alignment E=6.3e-112 PF14849: YidC_periplas" amino acids 85 to 353 (269 residues), 272.7 bits, see alignment E=5.7e-85 PF02096: 60KD_IMP" amino acids 357 to 544 (188 residues), 275.1 bits, see alignment E=3.2e-86 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 363 to 542 (180 residues), 247.7 bits, see alignment E=9.2e-78

Best Hits

Swiss-Prot: 98% identical to YIDC_RALPJ: Membrane protein insertase YidC (yidC) from Ralstonia pickettii (strain 12J)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 99% identity to rpf:Rpic12D_3458)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (554 amino acids)

>ABZR87_RS05360 membrane protein insertase YidC (Ralstonia sp. UNC404CL21Col)
MDIKRTILWVIFSLAVVLLFDNWQRANGHQSMFFPTPQTATTTAAAPGSTPAGDVPKSAS
TTAAAGSQAAPATGAASQAPASEKIVISTDLLRATIDTDGAIVTKLELLDQKDHDGNPMV
LFDRSVERTYLARSGLIGGDFPNHTTVFAASAGPRDLGTGNDVSITLTADKGGAKLAKTY
VFKRGSYVIDTRFDVTNDGTAPINPTLYLELARDGGAIEQSRFYSTFTGPAVYTDGDKFH
KITFADIDKGKAQVPAPTDSGWVAMVQHYFASAWIPADNVKREYYVNRVDNNFYRIGIQE
PLGTVAPGASVSATARLFAGPQQARMLEAITPGLDLVKDYGWLTIVAKPLFWLLEKIHAL
LGNWGWSIVALTVLIKLVFFPLSATSYRSMAKMKDLQPRMTAIRERHKGDPQKMNQEMMT
LYRTEKVNPLGGCLPIVIQIPVFMALYWALLSSVEMRGAPWIGWVHDLSTPDPFYILPVL
MAVSMFVQTKLNPTPPDPVQAKVMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSI
NRMLGTNNKAAPAK