Protein Info for ABZR87_RS02855 in Ralstonia sp. UNC404CL21Col

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 708 TIGR00484: translation elongation factor G" amino acids 1 to 705 (705 residues), 1204.3 bits, see alignment E=0 PF00009: GTP_EFTU" amino acids 9 to 288 (280 residues), 205.1 bits, see alignment E=1.9e-64 TIGR00231: small GTP-binding protein domain" amino acids 9 to 187 (179 residues), 106.6 bits, see alignment E=1.1e-34 PF03144: GTP_EFTU_D2" amino acids 331 to 398 (68 residues), 73.6 bits, see alignment E=3.5e-24 PF14492: EFG_III" amino acids 411 to 484 (74 residues), 118.7 bits, see alignment E=2.3e-38 PF03764: EFG_IV" amino acids 486 to 610 (125 residues), 154.3 bits, see alignment E=3e-49 PF00679: EFG_C" amino acids 613 to 699 (87 residues), 106.1 bits, see alignment E=2e-34

Best Hits

Swiss-Prot: 96% identical to EFG1_RALSO: Elongation factor G 1 (fusA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K02355, elongation factor G (inferred from 87% identity to bam:Bamb_0264)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (708 amino acids)

>ABZR87_RS02855 elongation factor G (Ralstonia sp. UNC404CL21Col)
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
ITITSAATTAFWKGMGGNYPEHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLKTRLKANPVPVVVPIGAEDGFQ
GVVDLLEMKAIIWDEASQGVKFEYHDIPANLVDVANEWREKMVESAAEASEELMEKYLGG
EELSRAEIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVQGIDE
NDEEKKLERKADDNEKFSALAFKIMTDPFVGQLIFFRVYSGKINSGDTVYNPVKQKKERL
GRILQMHANQREEIKEVLAGDIAAAVGLKDATTGDTLCDPSAPIILERMVFPEPVISQAV
EPKTKADQEKMGIALNRLAAEDPSFRVRTDEESGQTIISGMGELHLEILVDRMKREFGVE
ANIGAPQVAYRETIRKKVEDVEGKFVKQSGGRGQYGHAVITLEPADDEAKKAGKNFEFVD
AIKGGVIPREYIPAVEKGIVDTLPSGILAGFPVVDVKVTLTFGSYHDVDSNENAFRMAGS
MAFKEAMRRATPVLLEPMMAVEVETPEDYTGTVMGDLSSRRGIVQGMDDMVGGGKIIKAE
VPLSEMFGYSTSLRSQTQGRATYTMEFKQYAEAPKNIAEAVMAAKGTK