Protein Info for ABZR87_RS02005 in Ralstonia sp. UNC404CL21Col

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 transmembrane" amino acids 37 to 56 (20 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details amino acids 98 to 119 (22 residues), see Phobius details amino acids 125 to 151 (27 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 198 to 218 (21 residues), see Phobius details amino acids 252 to 276 (25 residues), see Phobius details amino acids 288 to 308 (21 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 344 to 367 (24 residues), see Phobius details amino acids 379 to 399 (21 residues), see Phobius details amino acids 411 to 429 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 27 to 237 (211 residues), 98.8 bits, see alignment E=3.6e-32 amino acids 262 to 433 (172 residues), 45.7 bits, see alignment E=4.7e-16 PF07690: MFS_1" amino acids 30 to 381 (352 residues), 88.8 bits, see alignment E=3.6e-29 amino acids 287 to 429 (143 residues), 48 bits, see alignment E=8.7e-17 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 32 to 423 (392 residues), 450.5 bits, see alignment E=2.8e-139

Best Hits

Swiss-Prot: 54% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to rpf:Rpic12D_2736)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>ABZR87_RS02005 MFS transporter (Ralstonia sp. UNC404CL21Col)
MPSSTSSAMATPAADPATDASRSRIVFASFIGTAIEFYDFYVYATAAALVIGPVFFPHGS
ATAQALSAFVTFGIAFIARPIGSFLFGHFGDRIGRKSTLVASLLVMGISTTLIGFVPGYD
SIGTLAPILLCILRFGQGIGLGGEWGGAALLATENAPAGKRGWFGMFPQLGPSVGFLASN
GLFFGLAIALSDEQFRSWGWRVPFLVSAVLVALGLYVRLKIAETPAFQAAIDRHERVKVP
VAELLARHWWPTLLGALAMVVCYTLFYISTVFSLSYGVGTLHFSRPSFLGLLCLAVVFMG
LATPLSAWASDRFGRKPVLIVGIVAAILSGFTMAPLLGSGQTPLVALFLIIELFLMGVTF
APMGALLPELFPTNVRYTGAGVSYNLGGILGASIAPYIAQKLAEQGGLSWVGMYVSAAAV
VSLIGVLCMRETRDTRLM