Protein Info for ABZR87_RS00210 in Ralstonia sp. UNC404CL21Col

Annotation: nitrite/sulfite reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 50 to 110 (61 residues), 58.8 bits, E=3.6e-20
  • amino acids 344 to 398 (55 residues), 44.5 bits, 1.1e-15
• PF01077: NIR_SIR
  • amino acids 119 to 273 (155 residues), 162 bits, E=8.2e-52
  • amino acids 411 to 550 (140 residues), 50.8 bits, E=1.3e-17

Best Hits

KEGG orthology group: K00381, sulfite reductase (NADPH) hemoprotein beta-component [EC: 1.8.1.2] (inferred from 99% identity to rpf:Rpic12D_2229)

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (12/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• assimilatory sulfate reduction I (4/4 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (7/10 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Protein Sequence (553 amino acids)

>ABZR87_RS00210 nitrite/sulfite reductase (Ralstonia sp. UNC404CL21Col)
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYYQRHAYMLRVAIPY
GHLRANQMRMLSHIAAEHDRGYGHFSTRQNIQYNWIELEQVPDILAKLASVEMHAIQTSG
NCIRNITTDQFAGVAPDEVIDARPLAEILRQWSTFIPEFAFLPRKFKIAVSASRQDRAVT
QLHDIGVYAYEKDGQTLLRILAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAVRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTITQAEFDRVAQFFAPPAYEKL
ADTDAGYEKALLENKAFARWVSRNVHPHRVPGYAAVTLSLKPGAALPPGDATAEQMALVA
DWSERFGFGEVRVAHEQNLILPDVKKHDLLELWQLAKEHGMATANIGLLTDIIACPGGDF
CSLANAKSIPIAQAIQARFDDLDYVHDLGELSLNISGCINSCGHHHVGNIGILGVDKHDE
EWYQVSLGGAQGNDSAIGKIIGPSFKAEEMPDVIERIIDTFVANRTEDELFIDTYHRIGM
TPFKERVYARAEA