Protein Info for ABZR86_RS13210 in Dyella japonica UNC79MFTsu3.2

Annotation: sensor histidine kinase KdpD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 884 transmembrane" amino acids 394 to 412 (19 residues), see Phobius details amino acids 418 to 434 (17 residues), see Phobius details amino acids 440 to 459 (20 residues), see Phobius details amino acids 471 to 489 (19 residues), see Phobius details PF02702: KdpD" amino acids 24 to 230 (207 residues), 310.5 bits, see alignment E=1.3e-96 PF00582: Usp" amino acids 249 to 361 (113 residues), 27.7 bits, see alignment E=8.7e-10 PF13493: DUF4118" amino acids 395 to 499 (105 residues), 72.8 bits, see alignment E=4.6e-24 PF00512: HisKA" amino acids 660 to 727 (68 residues), 53.5 bits, see alignment 5e-18 PF02518: HATPase_c" amino acids 774 to 881 (108 residues), 91.3 bits, see alignment E=1.4e-29

Best Hits

Predicted SEED Role

"Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)" in subsystem Potassium homeostasis (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2EQW0 at UniProt or InterPro

Protein Sequence (884 amino acids)

>ABZR86_RS13210 sensor histidine kinase KdpD (Dyella japonica UNC79MFTsu3.2)
MSDLSRDLRADALLDSVQEERHRRLKIFLGAAPGVGKTFAMLSAARELKRQGVDVVIGLV
ETHGRAETEALVDGLEVLPRRQVEYRGRDFTEFDLDAALARKPAVLLVDELAHRNLPGGR
HERRWQDIAELLDAGIEVYSALNVQHLESLNDQVRRITNVTVRETVPDAFLDRARDIVLV
DLPPRELIQRLKQGKVYVPETAAAALDAFFSPTNLAALRELAVDTVAGHVDSDLRGHMLA
RGGAMPVRRRVLAAIDGHGQSEYLVRVARRIAERRGAPWSVAFVDTGAGLDDKRREQLDA
AMRLARRLGGDAIVLRGHAVADEILAHADREGVGQILLGRTRERPLVRMLGRSLTQQLLR
RGAHLELTIIATPTERAQSRLRLRMPGGRGRRGEYLYATLAALVAFVLAFIADRYLSVAN
LALIFLTAVLVVAVRTRMAVAVYTATLCFVGYNFFFAPPRYTLMIANVDDVLAVCLFFVA
ALVCSRLATRLSSQVESMRAAHAQARALLALGQRLTASTDASGIRDVGAAALARALRCDA
AILMRDPGRVLQVASVSPRDFRLAAQDLGAADWSEKHAEPAGRYTDTLNAAPCWVLPLGS
ESRPLGVAAMRFAPEQRDLSPDQRSLAMAMVQDIGQALERARLADELEGARVQGETERLR
NALLSSVSHDLRSPLASMIGSAGTLSSYGEQLPSQERQELLDAILGEGQRLDRYIQNLLD
MTRLGHGTLKLNRDWTDVAEIVAAAVTRLHKLFPELKVDTMLPTGTLLLYVHPALIEQAL
FNILENAARFSPPGEAVRVLVRTEGDRLVLDVVDRGPGIPEDERARIFDMFYSVSRGDRA
PQGTGLGLAICRGMIGAHGGSVEALPGDGGGTTIRITLPLPTPP