Protein Info for ABZR86_RS05215 in Dyella japonica UNC79MFTsu3.2

Annotation: O-acetyl-ADP-ribose deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 176 PF01661: Macro" amino acids 21 to 132 (112 residues), 156.3 bits, see alignment E=1.6e-50

Best Hits

Swiss-Prot: 67% identical to Y2219_CHLTE: Macro domain-containing protein CT2219 (CT2219) from Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)

KEGG orthology group: None (inferred from 75% identity to vap:Vapar_1354)

MetaCyc: 47% identical to 2'-O-acetyl-ADP-ribose deacetylase, regulator of RNase III activity (Escherichia coli K-12 substr. MG1655)
RXN0-7013 [EC: 3.1.1.106]

Predicted SEED Role

"COG2110, Macro domain, possibly ADP-ribose binding module"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.106

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1XME2 at UniProt or InterPro

Protein Sequence (176 amino acids)

>ABZR86_RS05215 O-acetyl-ADP-ribose deacetylase (Dyella japonica UNC79MFTsu3.2)
MTAILRALRADITTLDLDAIVNAANSSLLGGGGVDGAIHRAAGPELVHECRLLGGCKTGD
AKITKGYRLPARHVIHTVGPVWRGGGEGEKALLTSCYRRSIEVAVAHGVSTLAFPSISTG
IYGYPIEQAAGVAVATVRAALEEAQAIREVIFCCFSPGDLTVYEGVLELPSKPAAR