Protein Info for ABZR86_RS04210 in Dyella japonica UNC79MFTsu3.2

Annotation: non-ribosomal peptide synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1705 transmembrane" amino acids 246 to 264 (19 residues), see Phobius details PF00668: Condensation" amino acids 1 to 450 (450 residues), 292.7 bits, see alignment E=9.7e-91 amino acids 1067 to 1508 (442 residues), 227.1 bits, see alignment E=7.6e-71 PF00501: AMP-binding" amino acids 472 to 816 (345 residues), 291.7 bits, see alignment E=1.5e-90 TIGR01733: amino acid adenylation domain" amino acids 492 to 890 (399 residues), 435.6 bits, see alignment E=8.6e-135 PF13193: AMP-binding_C" amino acids 874 to 949 (76 residues), 53.5 bits, see alignment (E = 7.5e-18) PF00550: PP-binding" amino acids 976 to 1035 (60 residues), 47.3 bits, see alignment (E = 4.1e-16)

Best Hits

Predicted SEED Role

"Siderophore biosynthesis non-ribosomal peptide synthetase modules @ Bacillibactin synthetase component F (EC 2.7.7.-)" (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1X3T7 at UniProt or InterPro

Protein Sequence (1705 amino acids)

>ABZR86_RS04210 non-ribosomal peptide synthetase (Dyella japonica UNC79MFTsu3.2)
MIPLSYAQQRLWFLQQLQGPNTLFNVPLLLRLRGVLHANALQTALDDVTNRHESLRTVFA
DVDGVGRQIVRGAGQARVPFELREVDAGALEAAQRQAAEHVFDLATEIPIRATLFRLRPD
EHVLLLLLHHIASDGSSLAPLIGDLATAYAARRRGQAPAWEPLPVQYADYSLWQREWMNE
ERDPDSSVARQIAYWTSTLAGLPEQLTIAADRPRPAHASHRGASVVFKVSASVHRRLREL
ARETQSSLFMALHAAVAALLSLHGAGEDLPIGTSVAGRDDEAMEAMVGLFVNLLVLRTDT
SGNPSFRELLRRARSVDLAAFSHQALPFERVVEAVNPLRTQGAHPLFQVALVLNNNASAA
SDFADLQLTFDFMHVAVAKYDLGFGFVEAFDEDGAPTGLSCDLEYALDLYEPDTAQRLVD
RFLRLLSEATGQPDLPLDRIDLLEESERRHVLENWNATAHPVPADNLADAFAAVATRTPD
AIAMRAGERAVTYGELDADANRLAHHLQSLGVGPDVLVGLCLERSPALLTATLAIVKAGA
AYLPLDPDYPAERLAQMLGETMSPVLVTQAELVDRLPAHWGALVVLEEEAEAIAQQPRTA
PGHALQAAHLAYAMYTSGSTGLPKGIAVTHRNVLDLALDRRWQDERQLRVLLHSPQVFDA
STYEIWVPLLSGREIVIAPPGKTDIDALARTIVEGQVTALFLTTALFRLIADMPDCLAGV
RTLWSGGEAASPQAFQKVLDACPHATVVHVYGPTETTTFATCHPLPPRWRADGGVPIGAP
MDNTRAYVLDRRLRLVPIGVPGELYIAGSGLARGYLRRPALTAERFVADPYGPPGSRLYR
TGDLVRWRADGQLVFVGRIDGQVKVRGFRIEPGEIEAALREQAGVAQAVVVAREDQPGHK
RLVGYVVAAPGQAPDPAALRRRLGERLPEYMVPVAIVLLEALPLTHNGKLDHKSLPAPDF
APAGRREPRTSQEVLLARLFADILGLEQVGMDESFFDLGGDSILAIQLKARAQNAGVAFD
LAHLFDHQSVARLAAIATFSVGGSARPVEAFELISEADRQCVPDHVEDAYPLSQVQAGMV
FYNRYDTASSVYHVVFCASMRLPFEEAMIRGVLDELALRHEVLRTSYDFDRYSVPLQLVH
RSARVPLVVDDLRGLDEAEREAAFDRWCGQEARSPFDVHVPPLLRVFVHRMTDVEFRFTL
SFNHAVLDGWSDASLVTEFMQRYQARLEGRALPAVPLPVRYRDYIALEQQAIASEATQRF
WRDMLAGYRPVEPQRSVLPARRGASHAQPEDFAVIRISQRTFEGLVDLAQQSQVPLKTIL
LSAHMAALSVLTGSRDVATAIVCHGRPEAVDAEKLIGLFLNAVFLRMRIGSVSWRGLIRD
VMEAESRLFPHRRYPLPAILGDSGLRNGIGVIFNYIHFHVYDQLDELGKKLDVGSGEGHS
AFPLGMDFQRDANGITATVTGHSHLYDRATLQRYADGYADILQTMAEAPDAPVGARSLLD
DDETARILGEWSADTRAVPGVSMPAGLRAERVRAYILDGTLQPVPAGVTGALYLAGDGIE
NHHAGSPAPTACSFIAHPFADGRRLYRTGDLASWSPDGSLMLHAPAERPAQGTDCAIDIE
RVDALLRAHPAIAHAASVLREDEPGRKQLVSYVITGPGQSVDADELRGCLSPVLPAHIAS
TLVITAPQRSAGHGARLDQETSMLW