Protein Info for ABZR86_RS03385 in Dyella japonica UNC79MFTsu3.2

Annotation: DHA2 family efflux MFS transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 52 to 73 (22 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 106 to 131 (26 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 167 to 189 (23 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details amino acids 233 to 251 (19 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 308 to 329 (22 residues), see Phobius details amino acids 336 to 355 (20 residues), see Phobius details amino acids 403 to 421 (19 residues), see Phobius details amino acids 475 to 498 (24 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 14 to 495 (482 residues), 390.7 bits, see alignment E=5.1e-121 PF07690: MFS_1" amino acids 19 to 413 (395 residues), 143.1 bits, see alignment E=5.4e-46

Best Hits

KEGG orthology group: None (inferred from 76% identity to pen:PSEEN2707)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I1ZFU8 at UniProt or InterPro

Protein Sequence (512 amino acids)

>ABZR86_RS03385 DHA2 family efflux MFS transporter permease subunit (Dyella japonica UNC79MFTsu3.2)
MSPVAHLSPGQKVFAFASMCLGMFIALLDIQIVSASLRDIGGGLSAGADDVAWIQTAYLI
AEIVVIPLSGWLSRVFSTRWLFAASAAGFTITSLLCGAAWDIQSMIVFRAAQGFLGGSMI
PTVFTTAFVFFEGKQRVIAAATIGAIASLAPTLGPTLGGWITDHYSWHWLFFINLVPGVF
VAIAVPLLVKIDEPDLSLLKSGDWAGIALIAVFLGCLEYTLEEGPRWNWLEDSTIRTTAW
VSLVAGVLFVWRGLTAEHPVVDLRALKDRNFALGCFFSFVTGIGLFATIYLTPLFLGRVE
GYSAFQIGKAVFSTGVFQILSIPVYAFLANRVDLRWLLMLGLALFTASMIEFMPITHDWS
STELLLPQALRGIGQQMAVPPTVTLTLGGLAPARLRFASGLFNLMRNLGGAMGIAACATI
LNDRANLHFYRLAEHLTPANEAMNSHWSDLSGATEASSAALRQLWQLTFREAQTLTYADA
FFCIMLCFAVATVMVPLMRKVQPPTGPSADAH