Protein Info for ABZR86_RS00270 in Dyella japonica UNC79MFTsu3.2

Annotation: serine hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00144: Beta-lactamase" amino acids 51 to 396 (346 residues), 222.5 bits, see alignment E=8.2e-70 PF11954: DUF3471" amino acids 434 to 538 (105 residues), 102.8 bits, see alignment E=1.2e-33

Best Hits

KEGG orthology group: None (inferred from 68% identity to xca:xccb100_1526)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1I2C9X4 at UniProt or InterPro

Protein Sequence (547 amino acids)

>ABZR86_RS00270 serine hydrolase (Dyella japonica UNC79MFTsu3.2)
MSRRVLSPRLACCAALLAFAVAPVRAQPPLQDAAPAAAASAALPAQLQDFQAYVDSARKQ
FDVPGIAVAIVKDGKVVLEQGFGEKETGKPGAVDAHTLFAIASNTKAFTAAALQILAERG
KLKMDDRVIDHLPWFQMSDPYVTREMRIRDLLAHRSGLGLGAGDLLYWPPTRYSTREVVE
RLREVPLATSFRSAYAYDNILFAVATLVIEQASGQSYADFIRDNLFKPVGMDESLVDMTY
LKPGMDVAMGHAKFDFKDLKPVPPMAWVNNPGAGGIYASVHDLARWMNVQLAGGALSDGK
QRVFKEESQKQMWSMLTPMRIGEPPVPELAATKPNFAGYGEGWFLSDYRGQRLVWHTGGW
PGMVSRLTLVPEFKLGVVVLTNQESGAAFNAVTYRVLDAYLGRDKTDWVAAYAAAVKKSE
DKADDSWKKHEAARDKHSKPSLAPARYAGTYRDPWYGDVVVAQEGGKLRLRFSKTPQLVG
TMTAWQHDTFVVRWDDRSLNADAFVSFTLDADGQIREARMQPVSPLTDFSFDFQDLRLAP
VKNAKEG