Protein Info for ABIE53_005770 in Paraburkholderia graminis OAS925

Annotation: Na+/H+ antiporter NhaD/arsenite permease-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 6 to 44 (39 residues), see Phobius details amino acids 51 to 74 (24 residues), see Phobius details amino acids 97 to 126 (30 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 247 to 267 (21 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 314 to 358 (45 residues), see Phobius details amino acids 376 to 407 (32 residues), see Phobius details amino acids 420 to 444 (25 residues), see Phobius details PF03600: CitMHS" amino acids 18 to 357 (340 residues), 151.8 bits, see alignment E=1.4e-48

Best Hits

KEGG orthology group: None (inferred from 78% identity to bph:Bphy_5880)

Predicted SEED Role

"Arsenic efflux pump protein" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>ABIE53_005770 Na+/H+ antiporter NhaD/arsenite permease-like protein (Paraburkholderia graminis OAS925)
MSAMQVYIVVGVFAAVILAIAFNVIDMAVAALVGMCVLIVLNILDEQDLLAAVRIAAGPI
SLLFGGMVVARILSTTGVFDLIGDVYLRATGGSGRRFLLLLIVVVAPLCALLPNATTVIL
LAPIIIRVAVALEVDIVLPMILTAIVSNAAGLLTLVGDPATFLVGSSIGMTFGNYLKHVS
LGGLLALAVVVPLLPFLMPDIWRVRRTLPPAEQRARIARPAYAGLSLAVLAAMMVLFVFG
EALPTRLVPPMVALIASALALLVGYAAKVEPTDNVLRDVDWKTLLFLACIFCLVQAMAKT
GLLQVMSVKLYELFGTRLTLVALAMIAGIGLLSSLLANVPVAAASIVMVKGYLVAAEFVP
EVALSDQFTQWPAPTIAVFVGMMFGATLGGNATLVGAAANIVAAGICAREGKPITFVRFL
RYGLPVTVAQLAASAVYVFALAHFMR