Protein Info for ABIE53_005610 in Paraburkholderia graminis OAS925

Annotation: MHS family proline/betaine transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 52 to 72 (21 residues), see Phobius details amino acids 81 to 99 (19 residues), see Phobius details amino acids 105 to 125 (21 residues), see Phobius details amino acids 146 to 169 (24 residues), see Phobius details amino acids 181 to 200 (20 residues), see Phobius details amino acids 234 to 256 (23 residues), see Phobius details amino acids 271 to 291 (21 residues), see Phobius details amino acids 299 to 316 (18 residues), see Phobius details amino acids 328 to 352 (25 residues), see Phobius details amino acids 364 to 387 (24 residues), see Phobius details amino acids 394 to 412 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 12 to 197 (186 residues), 66.3 bits, see alignment E=2.6e-22 amino acids 224 to 420 (197 residues), 48.1 bits, see alignment E=8.8e-17 PF07690: MFS_1" amino acids 14 to 278 (265 residues), 71.1 bits, see alignment E=8.2e-24 amino acids 240 to 417 (178 residues), 35.9 bits, see alignment E=4.4e-13

Best Hits

KEGG orthology group: None (inferred from 61% identity to bph:Bphy_6814)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>ABIE53_005610 MHS family proline/betaine transporter-like MFS transporter (Paraburkholderia graminis OAS925)
MKRPTTKRTLSAASIGNFGELYDFAVFGFSVPFIAAHFFPGSDPNAAILNTFAIYAVAFF
ARPVGGLMFGYLLDRVGRVKVLAITIWLMAGGTAMIGMLPTYESIGIAAPALLVACRFVQ
GLAVGGETTGSTSFVLESAPEKRRGFWVGIVYFFGNIPNAFVAFMLIGLQLLTGKAAYID
WAWRIPFLMGGLIGIVGYWVRRNLEDPEEYKLAAKKDPSATPLRVLTRSGLKSILCVSMI
MSLQSVASYYLLGFTYTFLVKQAGLESKMALLSNAIAIAAYAVTIPIGGALSDRFGRKTV
LTGGALWIALIAWLSIRLASNGTLLDAILGQALIAIGIGFYGSATFVASAEFFPTSFRAT
GHAIAYQATVAILGGTSPLVCAWLVRALHSPLAPGWYVTAVAAATVVLVRFIPETKDVDL
RTSIGGITPDSQSQFCPQPAASRSTGDAQ