Protein Info for ABIE53_005559 in Paraburkholderia graminis OAS925

Annotation: arylsulfatase A-like enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 683 transmembrane" amino acids 44 to 63 (20 residues), see Phobius details PF00884: Sulfatase" amino acids 83 to 545 (463 residues), 161.5 bits, see alignment E=1.5e-51

Best Hits

KEGG orthology group: K01130, arylsulfatase [EC: 3.1.6.1] (inferred from 88% identity to bpy:Bphyt_4474)

Predicted SEED Role

"Choline-sulfatase (EC 3.1.6.6)" in subsystem Choline Transport or Choline and Betaine Uptake and Betaine Biosynthesis (EC 3.1.6.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.6.6

Use Curated BLAST to search for 3.1.6.1 or 3.1.6.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (683 amino acids)

>ABIE53_005559 arylsulfatase A-like enzyme (Paraburkholderia graminis OAS925)
MLFSKPWLGGKWPVATISGSDNHGHITMQSSRSQRSTFPTVSRLRAVGAAVAGVIASVIA
LSACSDGVSPTPPVSAPVAAKRPNILYIMADDLGYSDIHAFGGEINTPNLDALVQSGRIL
TNHHTGTVCAITRAMLISGTDHHLVGEGTMGVPTDERKGLPGYEGYLNDRALSVAQLLKD
AGYHTYMAGKWHIGSGIAGSATGSGQTPDQWGFEHSYALLGGAATNHFAHEPAGSKNYTE
DGQYVQPGQPGQPGGAGGNPAVFYSTDFYTQRLISYIDSNRKDGKPFFAYAAYTSPHWPL
QVPEPYLHNYAGKYDAGYDVIRAARIARQKALGIIPADFNPYAGAAETLTATPASANNGT
TNAKYVSAVHSAAQGYSDYGPGFVNKSWASLSADEKKAQARYMEIYAGMVENLDHNIGLL
IQHLKDIGEYDNTFIMFQSDNGAEGWPIDSGADPRATDTANAAEPVYSTLGTDNGLQNAR
RLQYGLRWAEVSATPFRLTKGYSGEGGVSTPLIVRLPGQTTQKPALRVFTHVTDNTATFL
AVAGVTPPTQPAPALINSLTGVDQNKGKVIYNNRYVYPITGQSLLPVLTDQSNADVHTAS
FGDEAYGRGYLRSADGKWKALWTEPPLGPVDGHWQLYDMTSDRGETTDVAAQNPSIIDGL
VQQWNAYMSGVGGVEPLRPRGYY