Protein Info for ABIE53_005453 in Paraburkholderia graminis OAS925

Annotation: MHS family proline/betaine transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 61 to 85 (25 residues), see Phobius details amino acids 96 to 145 (50 residues), see Phobius details amino acids 165 to 183 (19 residues), see Phobius details amino acids 195 to 214 (20 residues), see Phobius details amino acids 245 to 264 (20 residues), see Phobius details amino acids 276 to 298 (23 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 335 to 354 (20 residues), see Phobius details amino acids 375 to 398 (24 residues), see Phobius details amino acids 405 to 423 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 26 to 237 (212 residues), 76.8 bits, see alignment E=1.7e-25 amino acids 231 to 395 (165 residues), 41.5 bits, see alignment E=8.7e-15 PF07690: MFS_1" amino acids 60 to 292 (233 residues), 66.6 bits, see alignment E=2e-22 amino acids 280 to 423 (144 residues), 38.4 bits, see alignment E=7.6e-14

Best Hits

Swiss-Prot: 38% identical to CITA_SALTI: Citrate-proton symporter (citA) from Salmonella typhi

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 87% identity to bge:BC1002_3458)

MetaCyc: 38% identical to propane-1,2,3-tricarboxylate-proton symporter (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-49

Predicted SEED Role

"Citrate-proton symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (430 amino acids)

>ABIE53_005453 MHS family proline/betaine transporter-like MFS transporter (Paraburkholderia graminis OAS925)
MSTDTATAAGTIAAPASNAHLSRLILATSIGNALEFYDLVVYGYFATVLSRLFFPAHDKT
VSLLLTLGTFALLYLARPVGALVLGSFSDRKGRKASLTLSIALMTLGTGLVALMPPYAAI
GVLAPIGIFASRLLQGFSAGGEFGSSTAFLIEHAPQRKGFMASWQFSSQGASTLLASAFG
AVLTSTLTQDQLEGWGWRIPFLFGMLIGPVGLYIRRRIDETPEFERAEKAASPVRELLAT
QKSRVLVSIGTLVLTTTANYMLLYMPTYASRQLGLAPWAGFVATLLAGFIMMVLTPIVGH
WSDKVGRTRIMLGAGVLFLVTVYPAFMLMNAHPSLVTLLAAVVWVALLKATYFAPIPALM
SELFPTRTRTTGMALGYNIGTTVFGGFTPLAVAALIAATGNNLAPGLYLMLAAVISLGTL
IWARARLNAR