Protein Info for ABIE53_005068 in Paraburkholderia graminis OAS925

Annotation: MHS family shikimate/dehydroshikimate transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 transmembrane" amino acids 24 to 49 (26 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 120 to 148 (29 residues), see Phobius details amino acids 161 to 184 (24 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 252 to 275 (24 residues), see Phobius details amino acids 287 to 309 (23 residues), see Phobius details amino acids 318 to 337 (20 residues), see Phobius details amino acids 343 to 362 (20 residues), see Phobius details amino acids 383 to 407 (25 residues), see Phobius details amino acids 414 to 430 (17 residues), see Phobius details PF00083: Sugar_tr" amino acids 29 to 425 (397 residues), 65.9 bits, see alignment E=3.4e-22 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 30 to 425 (396 residues), 468.2 bits, see alignment E=1.2e-144 PF07690: MFS_1" amino acids 57 to 301 (245 residues), 56 bits, see alignment E=3.3e-19 amino acids 266 to 429 (164 residues), 46.6 bits, see alignment E=2.4e-16

Best Hits

Swiss-Prot: 73% identical to SHIA_ECOLI: Shikimate transporter (shiA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to bug:BC1001_5179)

MetaCyc: 73% identical to shikimate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-27

Predicted SEED Role

"Shikimate transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>ABIE53_005068 MHS family shikimate/dehydroshikimate transporter-like MFS transporter (Paraburkholderia graminis OAS925)
MSTTLSPAATADNRIARSRARKAALGSFVGAVVDWYDFLLYGIVAALVFNAEFFPKVSPA
MGTLAAFATFGVGFLFRPLGGFVFGHFGDRLGRMRMLVLTVMMMGLSTAAIGLLPSFATI
GWLAPVLLVTLRAIQGFAVGGEWGGAALMAVESAPEKKKAFYSSGVQVGYGVGLVLATGL
VALISRSMDNASFMSWGWRLPFLFSVVLVLIAMWIRSSMEESQEFVEKVGAHGERRVRLP
IVEALLRHPKAFLLIIALRLAELFTMYIVTAFALNYSTANLHMPREFFLTIGLLVGAVSC
VTIPLFAMLADRFGRRRVYMIGALVGMFSAVPFFLALEARSTVWIVVFAVMLANIAHDMV
VSVQQPMFTELFGTEYRYSGAGVGYQVASVVGGGFTPFIAVALVSFAGGSWHPVAGYLAI
GCLISVLVAAKMKTGRSV